Resistance genes on the verge of plant–virus interaction

Sett, Susmita; Prasad, Ashish; Prasad, Manoj

doi:10.1016/j.tplants.2022.07.003

Cited by 45 publications

(27 citation statements)

References 116 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Resistance, together with tolerance [51], is one of the most relevant, effective and widespread defenses of plants against viruses. Thus, during the last few decades, understanding the molecular bases of plant resistance to viruses has been a long-standing goal in plant pathology [3,4]. ETI, resulting from the recognition of viral Avr proteins by plant R proteins, restricts virus infection to the entry sites in most cases, preventing systemic spread through the activation of an HR [3,17].…”

Section: Discussionmentioning

confidence: 99%

“…Plants are recurrently challenged by parasites in the wild and agroecosystems [1]. Because parasites have a negative impact on host growth and/or reproduction [2], plants have developed a variety of defense mechanisms to avoid infection and/or limit its consequences [3,4]. Plant defenses against parasites have far-reaching consequences for the fitness of both interacting organisms [5,6].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cucumber Mosaic Virus-Induced Systemic Necrosis in Arabidopsis thaliana: Determinants and Role in Plant Defense

Pagán

García‐Arenal

2022

Viruses

View full text Add to dashboard Cite

Effector-triggered immunity (ETI) is one of the most studied mechanisms of plant resistance to viruses. During ETI, viral proteins are recognized by specific plant R proteins, which most often trigger a hypersensitive response (HR) involving programmed cell death (PCD) and a restriction of infection in the initially infected sites. However, in some plant–virus interactions, ETI leads to a response in which PCD and virus multiplication are not restricted to the entry sites and spread throughout the plant, leading to systemic necrosis. The host and virus genetic determinants, and the consequences of this response in plant–virus coevolution, are still poorly understood. Here, we identified an allelic version of RCY1—an R protein—as the host genetic determinant of broad-spectrum systemic necrosis induced by cucumber mosaic virus (CMV) infection in the Arabidopsis thaliana Co-1 ecotype. Systemic necrosis reduced virus fitness by shortening the infectious period and limiting virus multiplication; thus, this phenotype could be adaptive for the plant population as a defense against CMV. However, the low frequency (less than 1%) of this phenotype in A. thaliana wild populations argues against this hypothesis. These results expand current knowledge on the resistance mechanisms to virus infections associated with ETI in plants.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cucumber Mosaic Virus-Induced Systemic Necrosis in Arabidopsis thaliana: Determinants and Role in Plant Defense

Pagán

García‐Arenal

2022

Viruses

View full text Add to dashboard Cite

show abstract

“…These models ignore the possibility of virus evolution, which is a major threat to the durability of genetic disease control mechanisms (Gallois et al (2018), Sett et al (2022)). Tolerant crops, by allowing pathogen replication, do not exert the same selection pressure (Råberg et al (2009)) and therefore may provide a more durable protection against yield loss (Bingham et al (2009), Newton (2016), Zhu et al (2004)).…”

Section: Discussionmentioning

confidence: 99%

Expanding growers’ choice of disease management options can promote suboptimal social outcomes

Murray-Watson

Cunniffe

2022

Preprint

View full text Add to dashboard Cite

Previous models of growers' decision-making during epidemics have unrealistically limited disease management choices to just two options. Here, we expand previous game-theoretic models of grower decision-making to include three control options: crop that is either tolerant, resistant, or susceptible to disease. Using Tomato Yellow Leaf Curl Virus (TYLCV) as a case study, we investigate how growers can be incentivised to use different control options to achieve socially-optimal outcomes. To do this, we consider the efforts of a "social planner" who moderates the price of crops. We find that subsidising tolerant crop costs the social planner more in subsidies, as its use encourages selfishness and widespread adoption. Subsidising resistant crop, however, provides widespread benefits by reducing the prevalence of disease across the community of growers, including those that do not control, reducing the number of subsidies required from the social planner. We then use Gini coefficients to measure equitability of each subsidisation scheme. This study highlights how grower behaviour can be altered using crop subsidies to promote socially-optimal outcomes during epidemics.

show abstract

“…MpSGF10B may belong to the extracellular LRR-only protein group. LRR-RLKs/RLPs and NBS-LRRs have been well studied and act in plant immune responses, such as various receptors and R-genes (Dievart et al, 2020;Sett et al, 2022). In contrast, extracellular LRR-only proteins have been poorly reported.…”

Section: Mpsgf10b Encodes An Extracellular Lrr-only Proteinmentioning

confidence: 99%

Comprehensive Analysis of Peptide-Coding Genes Identifies an LRR-only Microprotein That Regulates Reproductive Organs in Marchantia polymorpha

Kobayashi

Sugano

Tamura

et al. 2022

Preprint

View full text Add to dashboard Cite

In the past two decades, many plant peptides have been found to play crucial roles in various biological events by mediating cell-to-cell communications. However, a large number of small open reading frames (sORFs) or short genes capable of encoding peptides remain uncharacterized. In this study, we examined several candidate genes for peptides conserved between two model plants: Arabidopsis thaliana and Marchantia polymorpha. We examined the expression pattern in M. polymorpha and subcellular localization using a transient assay with Nicotiana benthamiana. We found that one candidate, MpSGF10B, was expressed in meristems, gemma cups, and male reproductive organs called antheridiophores. MpSGF10B has an N-terminal signal peptide followed by two leucine-rich repeat (LRR) domains and was secreted to the extracellular region in N. benthamiana and M. polymorpha. Compared with the wild type, two independent knockout mutants had an increased number of antheridiophores, which emerged from meristems. It was revealed in gene ontology enrichment analysis that MpSGF10B was significantly co-expressed with genes related to cell cycle and development. These results suggest that MpSGF10B may regulate the reproductive development in M. polymorpha. Our research should shed light on the unknown role of LRR-only proteins in land plants.

show abstract

Resistance genes on the verge of plant–virus interaction

Cited by 45 publications

References 116 publications

Cucumber Mosaic Virus-Induced Systemic Necrosis in Arabidopsis thaliana: Determinants and Role in Plant Defense

Cucumber Mosaic Virus-Induced Systemic Necrosis in Arabidopsis thaliana: Determinants and Role in Plant Defense

Expanding growers’ choice of disease management options can promote suboptimal social outcomes

Comprehensive Analysis of Peptide-Coding Genes Identifies an LRR-only Microprotein That Regulates Reproductive Organs in Marchantia polymorpha

Contact Info

Product

Resources

About