Resistance of Listeria monocytogenes, Escherichia coli O157:H7 and Campylobacter jejuni after exposure to repetitive cycles of mild bactericidal treatments

Rajković, Andreja; Šmigić, Nada; Uyttendaele, Mieke; Medić, Helga; Zutter, Lieven De; Devlieghere, Frank

doi:10.1016/j.fm.2009.06.006

Cited by 47 publications

(42 citation statements)

References 47 publications

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“…Decontamination techniques must also take into account the very strong ability of microorganisms to adapt themselves rapidly to their enviroment. Thus, the microorganisms that suffered sub-lethal stress factor can develop new resistance mechanisms (Hill et al, 2002;Lou & Yousef, 1997;Rajkovic et al, 2009;Rowan, 1999). This evolution is usually not abrupt but more gradual.…”

Section: Generalitiesmentioning

confidence: 99%

Decontamination of Solid and Powder Foodstuffs using DIC Technology

Allaf¹,

Besombes²,

Mih³

et al. 2011

Advances in Computer Science and Engineering

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Section: Generalitiesmentioning

confidence: 99%

Decontamination of Solid and Powder Foodstuffs using DIC Technology

Allaf¹,

Besombes²,

Mih³

et al. 2011

Advances in Computer Science and Engineering

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“…Although wastewater treatment plant has reduced much of those compounds, there are a number of biocides in the scale of ng/L to mg/L that still remaining [2][3]. Some researchers denote that sublethal concentration of remaining biocides found in the nature, particularly in the reclaimed water, may accumulate in the microbial cells and elicit microbial resistance on the biocides itself and some antibiotics, which may impact on the human health [4][5][6]. In the other hands, some toxic organic compounds such as the trihalomethanes, dioxins, and benzenes, which are known to be carcinogenic substances have been reported to be exist as the degradation products of those biocides and poisoning many aquatic organisms [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Investigation on the montmorillonite adsorption of biocidal compounds incorporating thermodynamical-based multicomponent adsorption isotherm

Ong¹,

Soetaredjo²,

Kurniawan³

et al. 2014

Chemical Engineering Journal

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“…The occurrence of stress-resistant variants in monoclonal populations of bacteria remains an important subject of debate, as some research groups have reported the isolation of such variants while others failed to demonstrate their presence and questioned their existence (1,3,5,16,17,19,24,29,31). In this study, we used a new strategy involving a kinetic modeling-based sampling scheme and an optimized stress challenge cycle method for the isolation of stress-resistant variants of L. monocytogenes.…”

Section: Discussionmentioning

confidence: 99%

Isolation of Highly Heat-Resistant Listeria monocytogenes Variants by Use of a Kinetic Modeling-Based Sampling Scheme

Boeijen

Francke

Moezelaar

et al. 2011

Appl Environ Microbiol

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Stable high-hydrostatic-pressure (HHP)-resistant Listeria monocytogenes LO28 variants were previously isolated and characterized. These HHP variants were also more resistant to heat. In addition, nonlinear heat inactivation kinetics pointed toward the existence of heat-resistant variants, although these could not be isolated so far. In this study, we used kinetic modeling of inactivation curves of two isolated HHP variants and their wild type, and this revealed that the probability of finding resistant variants should depend on the nature of the inactivation treatment and the time of exposure. At specific heat and HHP conditions, resistant LO28 and EGDe variants were indeed isolated. Resistant LO28 variants were even isolated after a heat inactivation at 72°C in milk, and these variants showed high resistance to standard pasteurization conditions. The increased resistance of part of the isolated LO28 and EGDe variants was due to mutations in their ctsR genes. For the variants whose ctsR genes and upstream regions were not altered, the mechanisms leading to increased resistance remain to be elucidated. This research showed the strength of kinetic modeling in unraveling the causes of nonlinear inactivation and facilitating the isolation of heat-resistant L. monocytogenes variants.Listeria monocytogenes can cause listeriosis in animal and human populations. Human listeriosis is a rare but severe disease and is one of the leading causes of death among patients with food-borne diseases in the United States. The estimated annual rate of invasive listeriosis in the United States is 3 cases and for countries within the European Union is 2 to 10 cases per million people per year (33). Recently, several European countries experienced an apparent increase in the incidence of listeriosis (13).A specific characteristic of L. monocytogenes that appears to be critical to its ability to cause human food-borne illness is its capacity to survive under harsh conditions. The occurrence of variants and the generation of population heterogeneity are factors that may contribute to the survival capacity of L. monocytogenes. Previous research showed that heterogeneity in L. monocytogenes populations (strains EGDe, LO28, and Scott A) affects resistance to high hydrostatic pressure (HHP). Inactivation of such heterogeneous populations resulted in survival curves with significant tailing, indicating the presence of an HHP-sensitive and an HHP-resistant fraction (32). Analysis of the cells that survived such HHP treatments revealed that the higher resistance of LO28 (32) and Scott A (17, 18) was a stable feature for part of the resistant fraction. Contrary to these results, no stable HHP-resistant isolates were obtained for EGDe (32). A significant fraction of the stably resistant variants of both Scott A and LO28 had an altered ctsR gene. This gene encodes CtsR, a DNA binding protein that regulates class III heat shock genes (7). The observed alterations in ctsR resulted not only in increased resistance to high pressure but also in increas...

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Resistance of Listeria monocytogenes, Escherichia coli O157:H7 and Campylobacter jejuni after exposure to repetitive cycles of mild bactericidal treatments

Cited by 47 publications

References 47 publications

Decontamination of Solid and Powder Foodstuffs using DIC Technology

Decontamination of Solid and Powder Foodstuffs using DIC Technology

Investigation on the montmorillonite adsorption of biocidal compounds incorporating thermodynamical-based multicomponent adsorption isotherm

Isolation of Highly Heat-Resistant Listeria monocytogenes Variants by Use of a Kinetic Modeling-Based Sampling Scheme

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