“…Also of concern is the knowledge that in similar eradication efforts, such as polio and guinea worm, disease incidence has fallen steeply during the early stages of the campaign but then leveled off due to nonlinear effects [4][5][6]. For example, malaria may be easily controlled in accessible, economically stronger regions, but remain refractory in remote, poorly resourced areas such as border regions where the per capita expenditure required for elimination surges.…”