Resolution of Diabetic Macular Edema After Surgical Removal of the Posterior Hyaloid and the Inner Limiting Membrane

Gandorfer, Arnd; Messmer, Elisabeth M.; Ulbig, Michael W.; Kampik, Anselm

doi:10.1097/00006982-200002000-00004

Cited by 311 publications

(206 citation statements)

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“…10 This is in contrast to plasmin-induced vitreoretinal separation, which resemble more closely spontaneous PVD, no such damage to the ILM was seen. 11 Damage to the ILM may change Muller cell physiology and so alter electrophysiological recovery as tested by ERG. 12 The less traumatic spontaneous PVD that occurred in three patients in the laser arm may have contributed to the thinning of the macula and to the visual improvement and thus narrowed the difference in the success rates for each treatment arm at 12 months.…”

Section: Change In Etdrs Visionmentioning

confidence: 99%

Diabetic macular oedema: pilot randomised trial of pars plana vitrectomy vs macular argon photocoagulation

Patel

Hykin

Schadt

et al. 2005

Eye

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Section: Change In Etdrs Visionmentioning

confidence: 99%

Diabetic macular oedema: pilot randomised trial of pars plana vitrectomy vs macular argon photocoagulation

Patel

Hykin

Schadt

et al. 2005

Eye

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“…Indeed, a subgroup of eyes with a taut premacular posterior hyaloid seemed to benefit from vitrectomy [26]. This strategy has been further developed with the introduction of peeling of the internal limiting membrane for the treatment of diffuse diabetic macular edema [10]. It is however still controversial whether this approach really improves vision in these eyes.…”

Section: Vitreoretinal Tractionmentioning

confidence: 99%

Surgical treatment of diabetic retinopathy

Helbig

Sutter

2004

Graefe's Arch Clin Exp Ophthalmol

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Several complications of advanced diabetic retinopathy can be treated surgically. Vitrectomy can clear media opacities, relieve traction on the retina, and makes adequate laser treatment of the retina possible. Removal of premacular vitreous may also improve diabetic macular edema. Instrumentation, understanding of the pathophysiology, surgical skills as well as supplementary pharmacotherapy have improved surgical results. Indications and timing for surgery have considerably changed in the past decades and the threshold for surgery has been continuously lowered, as vitrectomy became safer. The primary disease of the retinal microvasculature with capillary occlusion and retinal ischemia is still the limiting factor, responsible for disappointing functional results in anatomically successfully operated eyes.

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“…11,46 Much of the early literature, although uncontrolled, concentrates on patients with DMO in the presence of a taut thickened posterior hyaloid and these reports all suggest benefit in terms of improved acuity and reduced macular thickening. 2,[4][5][6][7]23 This is however a rare clinical presentation occurring in just 4% of eyes in our prevalence study. 46 Other than macular traction, potentially important predictors of outcome include the duration of macular oedema, extent of previous laser, degree of macular ischaemia, and amount of exudation.…”

Section: Introductionmentioning

confidence: 99%