Resolution of Gastric Outlet Obstruction After Eradication of Helicobacter pylori

Boer, W. A. De; Driessen, W. M. M.

doi:10.1097/00004836-199512000-00019

Cited by 45 publications

(22 citation statements)

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“…Some start anti-Hp therapy immediately [367] but in our experience the rapid response is actually related to the antisecretory drug therapy and not to the antibiotics and we prefer a more measured approach including endoscopy and biopsy to exclude malignancy, diagnose ulcer disease, and determine if Hp is present. Such patients respond rapidly to intravenous H2RA or PPI therapy.…”

Section: Medical Managementmentioning

confidence: 99%

“…Although there are no controlled studies, obstruction definitively occurs with Hp ulcers, and case reports indicate that, as expected in the absence of dense fibrosis, cure of Hp infection is associated with resolution of the obstruction [367,368]. Since deformities of the duodenum appear to resolve slowly following cure of Hp infection, complete resolution may take considerable time following cure of Hp infection.…”

Section: Medical Managementmentioning

confidence: 99%

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Peptic Ulcer Disease

Soll

Graham

2008

Textbook of Gastroenterology

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Section: Medical Managementmentioning

confidence: 99%

Section: Medical Managementmentioning

confidence: 99%

Peptic Ulcer Disease

Soll

Graham

2008

Textbook of Gastroenterology

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“…89 However, no large series has confirmed this mode of therapy. In the series by Gibson et al, 72 3 patients received HP infection therapy alone without dilation, and this was unsuccessful in avoiding operation.…”

Section: Gastric Outlet Obstructionmentioning

confidence: 99%

Management of Complicated Peptic Ulcer Disease

Behrman

2005

Arch Surg

149

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“…The relationship between H. pylori infection and peptic stenosis or gastric outlet obstruction has scarcely been investigated. Up to now, there are only a few reports showing a low prevalence of H. pylori infection in patients with peptic gastroduodenal stenosis and its resolution after the cure of the bacterium [31][32][33][34] . Furthermore, the definition of complications, the assessment of H. pylori infection, number and age of patients considered in these studies are heterogeneous, thus making it difficult to compare them and to draw conclusive statements.…”

Section: H Pylori-related Gastroduodenal Diseases Of Surgical Interestmentioning

confidence: 99%

Management ofHelicobacter pyloriInfection: Gastroenterological and Surgical Perspectives

Maconi¹,

Kurihara²,

Taschieri³

et al. 1999

Journal of Chemotherapy

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Diagnosis and treatment of Helicobacter pylori is a crucial point in the management of the different gastroduodenal disorders. Management involves the general practitioner and different specialists such as internists, gastroenterologists and surgeons. Among the most frequent H. pylori-related gastroduodenal disorders of medical interest are some diseases such as dyspepsia and gastroesophageal reflux, where the role of the bacterium is not well defined and therefore the importance H. pylori eradication is still controversial. On the contrary, the relationship of H. pylori and gastric and duodenal peptic ulcer is widely and definitively proven, and there are no doubts regarding the importance of curing the bacterium in these disorders. However, the surgical aspect of peptic ulcer, in particular the relevance and management of its complications, has not been widely investigated so far. In fact, the prevalence of H. pylori in perforated, bleeding and stenotic peptic ulcers seem to be lower that in non-complicated peptic ulcer, and whenever H. pylori eradication virtually prevents the re-bleeding of peptic ulcer in all cases, the effect of curing the bacterium in perforated and stenotic ulcers is still largely unknown. The management of H. pylori infection after gastric surgery is also still controversial. Most studies suggest that H. pylori can persist after gastric surgery whenever its incidence is much lower than that before operation. However it seems most unlikely that the infection plays a major role in the development of ulcer recurrence after gastric surgery or in the induction of gastric carcinoma. In any case, there are no convincing data that its cure may prevent the occurrence of gastric carcinoma following gastrectomy procedures.

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Resolution of Gastric Outlet Obstruction After Eradication of Helicobacter pylori

Cited by 45 publications

References 0 publications

Peptic Ulcer Disease

Peptic Ulcer Disease

Management of Complicated Peptic Ulcer Disease

Management ofHelicobacter pyloriInfection: Gastroenterological and Surgical Perspectives

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