Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography

Stein, Laura; Liang, John; Weinberger, Jesse

doi:10.1111/jon.12447

Cited by 5 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contemporary DUS studies have described thrombus changes between the acute and subacute phases and defined a ''hyperechogenic rim'' as a sign of imminent resolution. 21,22 Recent CTA studies defined the donut sign and correlated CFFT resolution in relation with advanced thrombus shape analysis. 11,12 Despite these efforts, only a few publications have attempted to answer which is the gold standard criteria for confirmatory diagnosis of CFFT, and the sensitivity and specificity of other diagnostic methods.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and management of carotid free-floating thrombus: A systematic literature review

Fridman

Lownie

Mandzia

2019

International Journal of Stroke

View full text Add to dashboard Cite

Background: There is no consensus regarding the management of carotid free-floating thrombi in patients with acute ischemic stroke and transient ischemic attack. Aims: This systematic review aims to (1) describe the current imaging methods for diagnosis of carotid free-floating thrombi and its associated risk factors, (2) estimate the proportion of carotid free-floating thrombi diagnosed in stroke patients, (3) estimate the proportion of carotid free-floating thrombi patients treated medically and surgically, and (4) evaluate 30-day outcomes. Methods: We searched MEDLINE, EMBASE, and manually for references reporting carotid free-floating thrombi from 1960 until June 2017. We estimated the frequency of carotid free-floating thrombi and evaluated 30-day outcomes using Cox regression. We defined the timing of surgical intervention as early (less than 72 h) and delayed (more or equal to 72 h). Summary of review: We retrieved 525 carotid free-floating thrombi cases from 58 case series and 83 case reports. Carotid free-floating thrombi were present in 1.53% of stroke patients. Carotid free-floating thrombi diagnosis was made by digital subtraction angiography (38.1%), carotid duplex ultrasound (29.5%), and computed tomography angiography (29.5%). The 30-day risk of transient ischemic attack, silent brain ischemia, any stroke or death was 17.1%. In multivariate analyses, there were no differences in outcome for any anticoagulation regime or timing of revascularization procedure. Conclusions: The diagnosis of carotid free-floating thrombi is more common due to the increased use of early noninvasive vascular imaging in transient ischemic attack and stroke. It poses a high short-term risk of stroke and death, but there is as yet no established treatment. The low quality of evidence in the carotid free-floating thrombi literature limits the interpretation of our results and warrants a large-scale prospective cohort study in carotid freefloating thrombi.

show abstract

Section: Discussionmentioning

confidence: 99%

Diagnosis and management of carotid free-floating thrombus: A systematic literature review

Fridman

Lownie

Mandzia

2019

International Journal of Stroke

View full text Add to dashboard Cite

show abstract

“…In addition, absence of significant contralateral atherosclerosis further supports the embolic origin of the ICA pathology (Fig F). Follow‐up with serial CDU examinations may document a progressive recanalization of the vessel, which may be reinforced by the introduction of anticoagulation …”

Section: Neurosonology Applications In Diagnosis and Risk Stratificationmentioning

confidence: 99%

The Role of Neurosonology in the Diagnosis and Management of Patients with Carotid Artery Disease: A Review

Kargiotis

Safouris

Magoufis

et al. 2018

Journal of Neuroimaging

View full text Add to dashboard Cite

Carotid artery disease (CAD) is a common cause of ischemic stroke with high rates of recurrence. Carotid endarterectomy (CEA) or carotid artery stenting (CAS) are highly recommended for the secondary prevention of symptomatic CAD during the first 14 days following the index event of transient ischemic attack or minor stroke. CEA or CAS may also be offered in selected cases with severe asymptomatic stenosis. Herein, we review the utility of neurosonology in the diagnosis and pre-/peri-interventional assessment of CAD patients who undergo carotid revascularization procedures. Carotid ultrasound may provide invaluable information on plaque echogenicity, ulceration, risk of thrombosis, and rupture. Transcranial Doppler or transcranial color-coded sonography may further assist by mapping collateral circulation, evaluating the impairment of vasomotor reactivity, detecting microembolization, or reperfusion hemorrhage in real time. Neurosonology examinations are indispensable bedside tools assisting in the diagnosis, risk stratification, peri-interventional monitoring, and follow-up of patients with CAD.

show abstract

Complete removal of massive thrombus trapped in the common carotid artery in stages

Ishida

Asakuno

2021

Interdisciplinary Neurosurgery

View full text Add to dashboard Cite

Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography

Cited by 5 publications

References 13 publications

Diagnosis and management of carotid free-floating thrombus: A systematic literature review

Diagnosis and management of carotid free-floating thrombus: A systematic literature review

The Role of Neurosonology in the Diagnosis and Management of Patients with Carotid Artery Disease: A Review

Complete removal of massive thrombus trapped in the common carotid artery in stages

Contact Info

Product

Resources

About