Resolution of optical isomers by high-performance liquid chromatography

The nature of chiral recognition: Is it a three-point interaction?

“…11 Here, too, the sterical ''fitness'' of the helical enantiomer to the accessible helical surface of the selectors (Fig. 3) automatically fulfills the requirements of an at least three-point interaction.…”

Synthesis of new polyconjugated molecules with biphenyl, dibenzothiophene, carbazole and phenanthrene units

“…The biaryl axis is the central building block in a very large number of various molecules such as natural and pharmacologically active products, 1 chiral reagents, 2 as the source of chiral phases for chromatography, 3 as inflexible "spacers" between two parts of a molecule, 4, 5 as the basis of liquid crystals 6 and fluorescent layers in OLEDs. 7 Different substituted biphenyls very often are used as suitable synthetic intermediates for synthesis heteroaromatic and polycyclic aromatic compounds.…”

DAB-Cy as an inexpensive and effective ligand for palladium-catalyzed homocoupling reaction of aryl halides

“…Moreover, by virtue of their excellent physical and chemical properties, they are also widely applied in monomers of conductive polymers [2], chiral host molecules for inclusion compounds [3], and chirality-recognition reagents for chromatography [4]. As for the synthesis of symmetrical biaryls, the main method is the Ullmann reaction [5], however, which requires equimolar amounts of copper and harsh reaction conditions (neat, >200°C).…”