A controlled-voltage Gas Electron Multiplier (GEM) can be used to block the re-injection of positive ions in large volume Time Projection Chambers. With proper choice of geometry, gas filling and external fields, good electron transmission can be obtained at very low GEM voltages; pulsed ion gating is then much easier than with conventional wire grids, requiring hundreds of volts. Gating schemes suited for the TPC detector planned for the International Linear Collider detector are described. The possibility of GEM-based DC-operated ion filters, exploiting the difference in diffusion properties of ions and electrons, is also discussed.