Resonant and scatterometric grating-based nanophotonic structures for biosensing

Auslender, Mark

doi:10.1117/1.2811923

Cited by 13 publications

(3 citation statements)

References 44 publications

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“…Figure 12 shows some increase in the enhancement factor as the wavelength increases but it does not scale exactly with the wavelength perhaps due to the strong dispersion and absorption of the metal. Absorption and dispersion are important for sensors based on spectroscopic interrogation rather than angular interrogation and particularly with the scatterometric grating based type sensors [26]. …”

Section: Resultsmentioning

confidence: 99%

Surface plasmon sensor with enhanced sensitivity using top nano dielectric layer

2009

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Increasing the sensitivity of surface plasmon resonance (SPR) sensors is important to enable controlling small concentrations of materials in liquid solutions or for gas sensing. Upon using a 10-15 nm top layer of dielectric film with a high value of the real part ′ ε of the dielectric function, on top of an SPR sensor in the Kretschmann configuration, the sensitivity is improved by few times. The imaginary part ′′ ε of the top nano layer permittivity needs to be small enough in order to reduce the losses and get sharper dips. The stability of the sensor is also improved because the nano layer is protecting the silver from interacting with the environment. In the near infrared range, the sensitivity is enhanced contrary to the standard SPR mode without top nanolayer. The calculated evanescent field is enhanced near the top layer -analyte interface, thus the enhancement is partially due to this fact and partially due to an increase of the interaction length as a waveguiding effect.

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Section: Resultsmentioning

confidence: 99%

Surface plasmon sensor with enhanced sensitivity using top nano dielectric layer

2009

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“…This choice also allows a √2 noise reduction through RGB coding. Further multi-parameter optimization of gratings micropads or other nanostructure might be realized [20,21], not necessary in the scope of this demonstration. It is illuminated from the glass side, so the incident angle on the RWG is not influenced by the analyte.…”

Section: Methodsmentioning

confidence: 99%

Resonant waveguide sensing made robust by on-chip peak tracking through image correlation

Bougot-Robin¹,

Wen²,

Bénisty³

2012

Biomed. Opt. Express

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We demonstrate a solution to make resonant-waveguide-grating sensing both robust and simpler to optically assess, in the spirit of biochips. Instead of varying wavelength or angle to track the resonant condition, the grating itself has a step-wise variation with typically few tens of neighboring “micropads.” An image capture with incoherent monochromatic light delivers spatial intensity sequences from these micropads. Sensitivity and robustness are discussed using correlation techniques on a realistic model (Fano shapes with noise and local distortion contributions). We confirm through fluid refractive index sensing experiments an improvement over the step-wise maximum position tracking by more than 2 orders of magnitude, demonstrating sensitivity down to 2 × 10−5 RIU, giving high potential development for bioarray imaging.

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“…To achieve the ideal LoD, one can optimize the system further such as using more divergence of the beam and using a camera with a larger number of pixels to decrease the pixel size. One can also use inverse scattering approaches such as theoretical calculation of reflectivity versus incidence angle, and fit it with experimental results 19 or parabolic fit near the dip minimum to achieve sub-pixel resolution. 20…”

Section: Sensitivity Of the Sensormentioning

confidence: 99%

Nanoprecision algorithm for surface plasmon resonance determination from images with low contrast for improved sensor resolution

Karabchevsky

Abdulhalim

2011

J. Nanophoton

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A forward-projection algorithm based on Radon transform for two-dimensional surface plasmon imaging was devised to achieve nanoscale precision in determining the surface plasmon signal. A diverging laser beam at the chosen frequency was used to overcome the angular scanning in the well-known Kretschmann configuration. Multichannel sensing with improved resolution was realized. The technique was also used to find the lateral resolution of the sensor using a patterned layer of 40-nm thick SiO 2 layer on top of the metallic surface. As a surface plasmon resonance signal detector, the use of the proposed Radon transform algorithm shows nanoprecision accuracy in cases of single and multichannel sensing. The method also provides the filtered output of the signal without any extra modification and therefore, it is nonsensitive to noise.

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Resonant and scatterometric grating-based nanophotonic structures for biosensing

Cited by 13 publications

References 44 publications

Surface plasmon sensor with enhanced sensitivity using top nano dielectric layer

Surface plasmon sensor with enhanced sensitivity using top nano dielectric layer

Resonant waveguide sensing made robust by on-chip peak tracking through image correlation

Nanoprecision algorithm for surface plasmon resonance determination from images with low contrast for improved sensor resolution

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