1 Vin~a In sti tute of Nu clear Sci ences, Uni ver sity of Bel grade, Bel grade, Ser bia 2 Fac ulty of Ap plied Ecol ogy, Singidunum Uni ver sity, Bel grade, Ser bia 3 Fac ulty of Ge og ra phy, Uni ver sity of Bel grade, Bel grade, Ser bia 4 Fac ulty of Tech nol ogy and Met al lurgy, Uni ver sity of Bel grade, Bel grade, Ser bia Sci en tific pa per http://doi.org/10.2298/NTRP1703281SThe sorp tion prop er ties of waste fa cade, brick, and as phalt sam ple to wards Sr(II), Co(II), and Ni(II) ions from sin gle and multicomponent so lu tions were in ves ti gated. The high est sorp tion ca pac ity was found for Ni(II) ions, while the most ef fec tive sorbent was fa cade. Simplex Cen troid Mix ture De sign was used in or der to in ves ti gate the sorp tion pro cesses of ions from so lu tions with dif fer ent com po si tion as well as the com pe ti tion be tween the cat ions. Based on the sta tis ti cal anal y sis re sults, the equa tions for data mod el ing were pro posed. Accord ing to the ob ser va tions, the in ves ti gated solid ma tri ces can be ef fec tively used for the liquid ra dio ac tive waste treat ment. Fur ther more, the ap plied meth od ol ogy turned out to be an easy and op er a tional way for the in ves ti ga tions of multicomponent sorp tion pro cesses.