Respiratory complications of Stevens-Johnson syndrome (SJS): 3 cases of SJS-induced obstructive bronchiolitis

Kaneko, Yoshiko; Seko, Yurie; Sotozono, Chie; Ueta, Mayumi; Sato, Satoshi; Shimamoto, Takayuki; Iwasaku, Masahiro; Uchino, Junichi; Hizawa, Nobuyuki; Takayama, K.

doi:10.1016/j.alit.2020.01.003

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…The prognosis of BO is generally poor, probably because of the irreversibility of the obstructive changes 11. The primary treatment for advanced BO is lung transplantation, although that treatment depends on the patient’s condition 12…”

Section: Discussionmentioning

confidence: 99%

Rare case of Stevens-Johnson syndrome with bronchiolitis obliterans as a chronic complication

et al. 2022

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A young girl in her teens presented with fever, rashes and various mucocutaneous symptoms. Flat erythematous macules were seen mainly on the limbs, without blisters or skin detachments. The lips were swollen with crusts and haemorrhage. The oral cavity and pharynx showed ulcerative lesions with exudate. Severe bilateral ocular lesions with pseudomembrane formation and corneal epithelial defects were present. Also, urogenital lesion and gastrointestinal symptoms with frequent haematochezia were observed. Her symptoms and pathological findings were consistent with Stevens-Johnson syndrome. She was treated with prednisolone and methylprednisolone pulse therapy. Her ocular and cutaneous symptoms improved without severe chronic complications. However, 1 month later, she developed dyspnoea, and a pulmonary function test revealed severe obstructive ventilation disorder. After discharge, she was regularly followed up for respiratory complications. High-resolution chest CT performed 9 months after onset revealed mosaic perfusions and bronchiectasis, consistent with bronchiolitis obliterans.

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Section: Discussionmentioning

confidence: 99%

Rare case of Stevens-Johnson syndrome with bronchiolitis obliterans as a chronic complication

et al. 2022

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“…Pasien dengan perubahan cepat bronkiektasis kistik tidak mungkin pulih dari gagal napas; transplantasi paru dapat dilakukan pada tahap awal SSJ. 17 Pasien dengan risiko gagal napas akut harus segera diintubasi dan diberi ventilasi mekanis. 18 Kebutuhan ventilasi mekanik pada pasien NET dewasa dikaitkan dengan mortalitas yang lebih tinggi.…”

Section: Sindromunclassified

Komplikasi Sindrom Stevens-Johnson (SSJ) dan Nekrolisis Epidermal Toksik (NET)

I Kadek,

Benny Wisan

2024

Cermin Dunia Kedokteran

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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening mucocutaneous reactions with severe skin involvement; may affect many internal organ systems with significant psychosocial complications. Several studies have documented physical complications associated with Stevens-Johnson syndrome and toxic epidermal necrolysis (TEN). SJS/TEN patients require multidisciplinary care to deal with psychological complications and reduced quality of life.

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End-Stage Respiratory Failure Secondary to Bronchiolitis Obliterans Syndrome Induced by Toxic Epidermal Necrosis, Also Known as Lyell Syndrome: A Case Report

Matar

Kessler

Olland

et al. 2021

Transplantation Proceedings

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Respiratory complications of Stevens-Johnson syndrome (SJS): 3 cases of SJS-induced obstructive bronchiolitis

Cited by 4 publications

References 10 publications

Rare case of Stevens-Johnson syndrome with bronchiolitis obliterans as a chronic complication

Rare case of Stevens-Johnson syndrome with bronchiolitis obliterans as a chronic complication

Komplikasi Sindrom Stevens-Johnson (SSJ) dan Nekrolisis Epidermal Toksik (NET)

End-Stage Respiratory Failure Secondary to Bronchiolitis Obliterans Syndrome Induced by Toxic Epidermal Necrosis, Also Known as Lyell Syndrome: A Case Report

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