Respiratory depression after alfentanil

Cassinello, Fernando; Peral, Á.L. Guerrero; Andueza, A.; Mourelle, I.

doi:10.1111/j.1365-2044.1992.tb02416.x

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Recurrent Respiratory Depression After Low Doses Of Alfentanil1

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1999

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“…A case of recurrent respiratory depression after the administration of alfentanil to a 45‐year‐old woman undergoing partial gastrectomy has been reported [1]. This phenomenon is well known with fentanyl and sufentanyl, but very few cases have been published with alfentanil [2,3].…”

Section: Recurrent Respiratory Depression After Low Doses Of Alfentanilmentioning

confidence: 99%

Correspondence

Calenda

Muraine

1999

Eur J Anaesthesiol

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Section: Recurrent Respiratory Depression After Low Doses Of Alfentanilmentioning

confidence: 99%

Correspondence

Calenda

Muraine

1999

Eur J Anaesthesiol

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Respiratory effects of intraoperative alfentanil infusion in post-abdominal hysterectomy patients: A comparison of high versus low dose

et al. 2000

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SummaryA number of reports have been published describing (recurrent) respiratory depression after the use of alfentanil intraoperatively. To evaluate the severity of respiratory depression after the administration of alfemanil, 49 patients undergoing general anaesthesia for abdominal hysterectomy were randomly allocated to one of three groups and studied in a double-blind manner. During surgery patients received no opioic:h (group 1), low dose (group 2) or high dose of alfentanil (group 3) . Postoperatively patients were monitored with pulse oximetry and respiratory inductive plethysmography. Postoperative pain was managed with PCA morphine.T hirty-nine patients completed the study. Respiratory depressar1t effects were found in all three groups. A hiRher number of apnoeas (at 60 minutes in group 1: 3.3 ± 1.6; group 2: 3.5 ± 1.8; group 3: 12.2 ± 2.8) and a higher morphine consumption was found in group 2 when compared with group l and 3. o differences were found among the groups in the other respiratory parameters or in terms of the number of patients with respiratory depression at any one time. No cases of dear-t.-ut recurrent respiratory depression were identified.

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Recurrent respiratory depression after low doses of alfentanil

Calenda¹,

Muraine²

1999

European Journal of Anaesthesiology

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Respiratory depression after alfentanil

Cited by 4 publications

References 5 publications

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Respiratory effects of intraoperative alfentanil infusion in post-abdominal hysterectomy patients: A comparison of high versus low dose

Recurrent respiratory depression after low doses of alfentanil

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