Respiratory Disorders and Quality of Sleep in Patients on the Waiting List for Lung Transplantation

Pascual, Natalia; Jurado, Bernabé; Rubio, Juan Manuel; Santos, Francisco; Lama, R.; Cosano, A.

doi:10.1016/j.transproceed.2005.02.043

Cited by 13 publications

(3 citation statements)

References 4 publications

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“…40 Another study, in which AHI ≥ 10 was considered abnormal, examined 17 patients on a lung transplant waiting list and compared them to healthy controls. 22 The waiting list patients had a mean AHI (6.13 ± 6 events/h) that was similar to the control group. These findings would suggest that SDB develops after transplantation, but requires confirmation in a prospective study.…”

Section: Discussionmentioning

confidence: 67%

“…The apnea-hypopnea index (AHI) was defined as the number of apneas and hypopneas per hour of sleep. To make our results comparable to those of the 2 most relevant studies on sleep apnea prevalence in lung transplant candidates or recipients by Malouf et al 21 and Pascual et al, 22 we used the same AHI of ≥ 10 as they did to identify subjects as having SDB. Subjects were further characterized as having obstructive sleep apnea (OSA) if ≥ 50% of the respiratory events of the night were obstructive, or having central sleep apnea (CSA) if ≥ 50% of the respiratory events of the night were central.…”

Section: Sleep Studiesmentioning

confidence: 99%

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Prevalence of Sleep Disordered Breathing in Lung Transplant Recipients

Naraine

Bradley

Singer

2009

Journal of Clinical Sleep Medicine

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Scientific inveStigAtionSStudy objectives: Weight gain and obesity are common after lung transplantation. Despite associations between these conditions and sleep disordered breathing (SDB) in the general population, the prevalence and clinical impact of SDB in lung transplant recipients is unknown. The study objective was to determine the prevalence and clinical correlates of SDB in a cohort of lung transplant recipients. Methods: Single-center cross-sectional study. Overnight polysomnography, sleep questionnaires, and anthropomorphic measurements were conducted on 24 lung recipients transplanted at least one year previously. The primary outcome was the prevalence of SDB, defined as an apnea-hypopnea index (AHI) ≥ 10 per hour. Results: The prevalence of SDB was 63%. Obstructive sleep apnea (OSA) was observed in 38% and central sleep apnea (CSA) in 25%. Among all subjects, the mean AHI was 19.7 ± 24.4 events/hour and the average weight gained after transplant was 10.5 ± 12.3 kg. Sub-jects with SDB had a higher systolic blood pressure (135 ± 12 vs. 124 ± 13 mm Hg, p = 0.045), body mass index (BMI) (28.2 ± 3.7 vs. 24.0 ± 4.0 kg/m 2 , p = 0.008) and arousal index (28.0 ± 26.9 vs. 10.4 ± 6.4 per hour, p = 0.025) compared to the non-SDB group. Cyclosporine use was associated with CSA (p = 0.006). Recipients with OSA had a greater change (pre to post transplant) in BMI (5.8 ± 4.6 vs. 2.0 ± 2.9 kg/m 2 , p = 0.05) compared with non-SDB subjects. Conclusions: Sleep disordered breathing is highly prevalent after lung transplantation. Polysomnography should be considered in lung transplant recipients, especially if they have gained weight.

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Section: Discussionmentioning

confidence: 67%

Section: Sleep Studiesmentioning

confidence: 99%

Prevalence of Sleep Disordered Breathing in Lung Transplant Recipients

Naraine

Bradley

Singer

2009

Journal of Clinical Sleep Medicine

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“…Kaliteli bir uyku için toplam uyku süresinin yeterli olması, uyku etkinliğinin yüksek olması, uyanıklık süresinin düşük olması, uykunun sık sık uyanıklık ile bölünmemesi, REM ve non-REM evre 3-4 sürelerinin ve uyku içindeki oranlarının normal sınırlar içinde olması gerekmektedir (17). İAH'de uyku kalitesinde bozulma hastaların öksürükle veya desatürasyonla birlikte arousal yanıtının artmasına bağlanmaktadır (18). Çalışmamızda, uyku kalitesi ve gündüz uykululuğu açısından farkındalığı olmayan İAH hastaların %44'ünde PUKİ ile ölçülen subjektif uyku kalitesi kötü bulundu, hastaların %52'sinde EUS ile gündüz uykululuğu saptandı.…”

Section: Sonuçunclassified

Evaluation of Sleep Related Breathing Disorders and Obstructive Sleep Apne Syndrome in Interstitial Lung Patients

Hanci¹,

Alpaydın²,

İtil³

et al. 2016

jtsm

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Objective:Interstitial lung disease (ILD) may create sleep disturbances due to chronic disease-related stress, respiratory abnormalities and adverse effects of treatment. We aimed to determine the quality of sleep in ILD patients, and the incidence of Obstructive sleep apnea syndrome (OSAS) in these patients. Materials and Methods: Taken to this study were 52 patients who were followed up in our center due to ILD. Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI) were applied to the patients. Spirometry and diffusion test were performed. Polysomnography (PSG) was performed to 27 patients whose ESS were more than or equal to 10. Results: Demographic characteristics, body mass index, spirometry and diffusion measurements, PSQI global score and the sub-components of it didn't show difference according to ESS daytime sleepiness.

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Lung Diseases

Tobias¹,

Won²

2019

Handbook of Sleep Disorders in Medical Conditions

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Respiratory Disorders and Quality of Sleep in Patients on the Waiting List for Lung Transplantation

Cited by 13 publications

References 4 publications

Prevalence of Sleep Disordered Breathing in Lung Transplant Recipients

Prevalence of Sleep Disordered Breathing in Lung Transplant Recipients

Evaluation of Sleep Related Breathing Disorders and Obstructive Sleep Apne Syndrome in Interstitial Lung Patients

Lung Diseases

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