2015
DOI: 10.1007/s12663-015-0772-7
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Respiratory Distress Secondary to Rhabdomyosarcoma of the Tongue and Co-existent Choanal Atresia

Abstract: Whilst rhabdomyosarcoma (RMS) is the third most common solid tumour in children, congenital RMS of the tongue is extremely rare and usually present as painless progressive mass since birth (Dagher and Helman in Oncologist 4:34-44, 1999; Childs and Goudy in Int J Pediatr Otorhinolaryngol 5:126-128, 2010). In neonates, presentation with respiratory distress is unexpected as neonates are preferential nasal breathers and restricted oral breathing due to tumour usually poses no problem. We herein report a case of … Show more

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(2 citation statements)
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“…We reviewed all the cases reported in the English language on tongue RMSs in pediatrics using the PubMed engine. Twenty cases were reported, including our case, summarized in Table 2 [7,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. Ten (50%) of the cases were female.…”
Section: Discussionmentioning
confidence: 99%
“…We reviewed all the cases reported in the English language on tongue RMSs in pediatrics using the PubMed engine. Twenty cases were reported, including our case, summarized in Table 2 [7,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. Ten (50%) of the cases were female.…”
Section: Discussionmentioning
confidence: 99%
“…We note that MST loss led to a propensity for tumors in the tongue, suggesting a role for MST activity in the muscle of the tongue. There are many reports of RMS arising in the tongue [Ref (21) and references therein], and an increasing body of literature on the role of Hippo regulation in craniofacial development (22).…”
Section: Discussionmentioning
confidence: 99%