Respiratory infections caused by Branhamella catarrhalis

Sarubbi, Felix A.; Myers, James W.; Williams, Jennifer J.; Shell, Charles G.

doi:10.1016/0002-9343(90)90254-b

Cited by 51 publications

(38 citation statements)

References 13 publications

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“…This is comparable to the findings by Sarubbl et al [11]. The majority of our patients (77.5%) had underlying pulmonary conditions such as chronic bronchitis, bronchial asthma, bronchiectasis, and carcinoma of the bronchus; this is consistent with observations from elsewhere [14].…”

Section: Discussionsupporting

confidence: 93%

“…At Qatif Central Hospital, eastern region of Saudi Arabia, we found that Branhamella catarrhalis is the third most common cause of infective exacerbation of chronic pulmonary disease after Haemophilus influenzae and Streptococcus pneumoniae [17]. This finding is in agreement with reports from Western countries [10,11]. However, our findings are at variance with previous studies from Riyadh Armed Forces Hospital [12] and hospitals located in Jeddah [13], in which B. catarrhalis was not reported as a cause of pneumoniae.…”

Section: Discussionsupporting

confidence: 91%

“…The isolation rate of B. catarrhalis has been reported by others [10][11][12][13][14][15] to be higher in winter and spring; in this study, however, there was no significant increase in the rate of isolation during the cold season.…”

Section: Discussioncontrasting

confidence: 60%

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Bronchopulmonary Infection due to Moraxella (Branhamella) Catarrhalis at Qatif Central Hospital

et al. 1992

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Moraxella (Branhamella) catarrhalis is now recognized as an important cause of respiratory tract infections. Over a two year period, Moraxella (Branhamella) catarrhalis was isolated in pure culture from 3.4% of the sputums collected from patients with symptoms of acute respiratory tract infections. It was the third most important pathogen isolated after Haemophilus influenzae and Streptococcus pneumoniae; 77% of the patients had an underlying chronic pulmonary condition. Prevalence, antibiotic sensitivity, and treatment options, will be discussed. It has generally been regarded as an oropharyngeal commensal. In the early 1980s, B. catarrhalis began to be recognized as an increasingly important pathogen when it was cultured from aspirates from infected sinuses [1] and from the middle ear in children with otitis media [2]. Its association with bronchopulmonary infections in older patients with underlying pulmonary disease has been particulary well noted [3,4].At Qatif Central Hospital in the eastern region of Saudi Arabia, there has been a marked increase in the isolation of B. catarrhalis from the sputum of patients with symptoms of bronchopulmonary infection.In this report, the prevalence and antibiotic susceptibility of B. catarrhalis in respiratory infection is described. To the best of our knowledge, this is the first report from Saudi Arabia about this potential pathogen. MethodsOur study is based on sputum cultures obtained at Qatif Central Hospital between January 1989 and December 1990; cultures positive for B. catarrhalis were identified.All sputa were screened for acceptability using published cellular criteria [5,6]. A purulent part of each sputum specimen received was examined with gram film inoculated on blood agar and heated blood plates.The plates were incubated in 7% carbon dioxide for 18 hours. Only moderate or profuse growth in the primary plate was reported. Moraxella (Branhamella) catarrhalis was identified by the presence of extraleucocytes and intraleucocytes gram negative diplococci in the gram film, by colonial and morphological appearance and by positive oxidase and catalase reactions. The identification was confirmed with the rapid carbohydrate utilization test [7].All strains were tested for deoxyribonuclease activity [8]. Tests for sensitivity to penicillin, ampicillin, amoxycillin-clavulanate, tetracycline, chloramphenicol, cotrimoxazole, erythromycin, cefuroxime, ceftrizoxime, and ceftriaxone were performed using the Stokes disc diffusion method [9].A retrospective study of the case notes and radiology reports was made for all patients who yielded a pure culture of B. catarrhalis in the sputum. Mixed infections in which organisms such as Strept. pneumoniae or H. influenzae were isolated along side B. catarrhalis were excluded from this study.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 91%

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Bronchopulmonary Infection due to Moraxella (Branhamella) Catarrhalis at Qatif Central Hospital

et al. 1992

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“…catarrhalis se ha identificado principalmente asociado a tres condiciones clínicas: otitis media en niños, así como neumonía y bronquitis en adultos con enfermedad pulmonar crónica y sinusitis. 4,5,7,8 La colonización durante la infancia es un fenó-meno frecuente, sobre todo en menores de dos años. 13 La prevalencia de colonización que se encontró en los niños del Distrito Federal fue similar a los porcentajes notificados en niños de otros países de Europa y Asia y en Estados Unidos de América, 8,14,15 existiendo un predominio en los menores de tres años.…”

Section: Discussionunclassified

“…En los últimos veinte años se ha identificado como germen causal en una diversidad de procesos infecciosos como otitis media, sinusitis, conjuntivitis, bronconeumonía, tos persistente, laringitis y queratitis. [4][5][6][7][8][9] Asimismo, se ha identificado en otitis media en el tercer lugar de los agentes aislados. 10,11 Además, puede dar lugar a enfermedades sistémicas como bacteremia, sepsis, endocarditis, meningitis e infección urinaria complicada en pacientes con enfermedad neoplásica, con enfermedad pulmonar crónica y en aquellos con alteraciones del sistema inmunológico.…”

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