Respiratory rate-OXygenation index: enhancing decision-making and predicting rehabilitative outcomes in critical respiratory settings

Panzuti, Giulia; Vega, María Laura; Polastri, Massimiliano

doi:10.12968/ijtr.2021.0034

International Journal of Therapy and Rehabilitation

2021

DOI: 10.12968/ijtr.2021.0034

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Respiratory rate-OXygenation index: enhancing decision-making and predicting rehabilitative outcomes in critical respiratory settings

Giulia Panzuti

María Laura Vega

Massimiliano Polastri³

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2024

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Comparison of Modified ROX Index Score and ROX Index Score for Early Prediction of High Flow Nasal Oxygen Therapy Outcome in Patients with Acute Respiratory Failure: A Prospective Observational Cohort Study

Bhatia,

Kothari,

Mohammed

et al. 2024

Indian Journal of Critical Care Medicine

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A bstract Background We compared the modified ROX index and ROX index scores in earlier predictions of high-flow nasal oxygen (HFNO) therapy outcomes in patients with acute respiratory failure. Methods We conducted a prospective observational study on 151 acute respiratory failure patients initiated on HFNO therapy. The primary objective of this research was to compare the modified ROX index and ROX index to investigate which score predicted HFNO treatment outcome earlier. Results The modified ROX index score had better predictive power than the ROX score at different time points, especially one hour following the start of HFNO therapy (AUC 0.790; 95% CI: 0.717–0.863; p < 0.001). For the ROX Index at 1 hour, the ideal cut-off value for HFNO outcome was 4.36 (sensitivity: 72.6%, specificity: 53.9%), and for the modified ROX index at 1 hour, it was 4.63 (sensitivity: 74.2%, specificity: 69.7%). The presence of various comorbidities didn't show any change in ROX-HR cut-off values. Conclusion The modified ROX index is a better predictor of the success of HFNO therapy than the ROX index. Furthermore, the presence of any comorbidities did not affect modified ROX index cut-off values or the outcome of HFNO therapy. How to cite this article Sarkar AG, Sharma A, Kothari N, Goyal S, Meshram T, Kumari K, et al . Comparison of Modified ROX Index Score and ROX Index Score for Early Prediction of High Flow Nasal Oxygen Therapy Outcome in Patients with Acute Respiratory Failure: A Prospective Observational Cohort Study. Indian J Crit Care Med 2024;28(9):842–846.

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Comparison of Modified ROX Index Score and ROX Index Score for Early Prediction of High Flow Nasal Oxygen Therapy Outcome in Patients with Acute Respiratory Failure: A Prospective Observational Cohort Study

Bhatia,

Kothari,

Mohammed

et al. 2024

Indian Journal of Critical Care Medicine

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Respiratory rate-OXygenation index: enhancing decision-making and predicting rehabilitative outcomes in critical respiratory settings

Cited by 1 publication

References 16 publications

Comparison of Modified ROX Index Score and ROX Index Score for Early Prediction of High Flow Nasal Oxygen Therapy Outcome in Patients with Acute Respiratory Failure: A Prospective Observational Cohort Study

Comparison of Modified ROX Index Score and ROX Index Score for Early Prediction of High Flow Nasal Oxygen Therapy Outcome in Patients with Acute Respiratory Failure: A Prospective Observational Cohort Study

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