Respiratory symptoms in children and exposure to pesticides

Salameh, Pascale; Baldi, Isabelle; Brochard, Patrick; Rahérison, Chantal; Saleh, Bernadette Abi; Salamon, Roger

doi:10.1183/09031936.03.00107403a

Cited by 107 publications

(78 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…14 The prevalence of symptoms of chronic respiratory illness (22%) was consistent with Norway study, 15 but higher than the Lebanese study. 20 This could be explained by the younger age of the interviewees in the Lebanese study. Another study compared the results of two different databases using three criteria: the prevalence of airways obstruction was 13% according to the European criterion, 45% according to the American criterion, and 23% according to clinical 25 The latter result was in agreement with the present study.…”

Section: Discussionmentioning

confidence: 99%

“…26 In Lebanon, a study using similar criteria to those of the present study, revealed an association between several types of pesticide exposure -domestic, environmental, and occupational (parents) -and respiratory symptoms among rural students. 20 The use of multivariate analysis based on a hierarchical model revealed the independent effects of several agricultural activities. Grouping pesticide exposure in different forms to what a subject is exposed to showed that the group of farmers not exposed to pesticides had a high prevalence of respiratory symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…23 Chronic respiratory disease was defined as the presence of at least one of the following symptoms: cough or phlegm during most days of the week for three or more months per year, recurrent wheezing (most days and nights), or two or more episodes of wheezing with shortness of breath. 20 Crude analyses evaluated associations through Chisquare and linear trend tests. The employees showed better socioeconomic conditions than farm owners, considering that all agricultural and socioeconomic indicators reflected the characteristics of the rural property and the employees (7% of the sample) worked in the richest farms.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Pesticides and respiratory symptoms among farmers

et al. 2005

View full text Add to dashboard Cite

ObjectiveDespite the intensive use of pesticides in agriculture there are few studies assessing the risk of respiratory conditions from this exposure. The study aimed at quantifying the prevalence of respiratory symptoms among farmers and evaluating its relationship with occupational use of pesticides and the prevalence of respiratory symptoms. Methods A cross-sectional study was conducted among 1,379 farmers from two municipalities of Southern Brazil in 1996. Frequency and type of chemical exposure and pesticide poisoning were recorded for both sexes. All subjects aged 15 years or older with at least 15 weekly hours of agricultural activity were interviewed. An adapted questionnaire developed by the American Thoracic Society was used for the assessment of respiratory symptoms. Multivariate logistic regression analysis was carried out. Results More than half (55%) of interviewees were male. The prevalence of asthma symptoms was 12% and chronic respiratory disease symptoms was 22%. Higher odds ratios for both asthma (OR=1.51; 95% CI: 1.07-2.14) and chronic respiratory disease (OR=1.34; 95% CI 1.00-1.81) symptoms were found in women. Logistic regression analysis identified associations between many forms of exposure to pesticides and increased respiratory symptoms. Occurrence of pesticide poisoning was associated with higher prevalence of asthma symptoms (OR=1.54; 95% CI: 1.04-2.58) and chronic respiratory disease symptoms (OR=1.57; 95% CI: 1.08-2.28). ConclusionsIn spite of causality limitations, the study results provide evidence that farming exposure to pesticides is associated with higher prevalence of respiratory symptoms, especially when the exposure is above two days per month. Resumo Objetivo

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Pesticides and respiratory symptoms among farmers

et al. 2005

View full text Add to dashboard Cite

show abstract

“…The acute toxic effects are easily recognized, while the effects of long-term exposure at low doses are hard to diagnose (Chakraborty et al, 2009). These include: temporary and nonspecific symptoms such as eye irritation, dermatitis, asthma, peripheral neuropathy, chronic neurobehavioral motor dysfunction, burning sensation in the face, headache, dizziness, respiratory problems and sialorrhoea, and even chronic diseases such as cancer as well as disorders of the reproductive system (Ohayo-Mitoko et al, 2000;Miranda et al, 2002;Sanborn et al, 2002;Safi, 2002;Salameh et al, 2003;Del Prado-Lu, 2007). Accidental and intentional poisoning have been better studied than occupational exposure, where biological monitoring of workers exposed to pesticides has been widely recommended both to prevent poisoning and for epidemiological studies (Hofmann et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Pesticide use and cholinesterase inhibition in small-scale agricultural workers in southern Brazil

Nerilo

Martins

Nerilo³

et al. 2014

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

A controlled cross-sectional study of family growers of fruit and vegetables was conducted between October 2009 and October 2010 to characterize the use of pesticides, establish the socio-demographic profile, and analyze cholinesterase activity in small-scale agricultural workers in Southern Brazil. Data was collected for 173 workers and 179 controls. A structured questionnaire was applied collecting socio-demographic information and determining knowledge and work practices in relation to pesticide use. The benchmarks for total cholinesterase (ChEs) and butyrylcholinesterase (BuChE) were obtained from the average enzymatic activity of the occupationally unexposed group (control). The mean age of the exposed population was 40.0 ± 11.2 years. The symptoms differed significantly (p<0.05) between the exposed and unexposed populations. Forty (23.1%) workers showed symptoms associated with exposure to pesticides. The average value of enzymatic activity in the occupationally unexposed group for ChEs was 6.3 μmol/mL/min among males and 5.6 μmol/mL/min among females while for BuChE was 2.4 μmol/mL/min among males and 2.0 μmol/mL/min among females. Eight (4.6%) workers had high inhibition (>30%) of ChEs activity, whereas no workers showed high inhibition (>50%) of BuChE. Potential factors involved include gender, education, pesticide orientation, exposure, and hygiene measures.Uniterms: Pesticides/use. Pesticides/occupational exposure. Cholinesterase/evaluation/exposure to pesticides. Agricultural workers/exposure to pesticides. Environmental health. Brazil/southern/ environmental health.Realizou-se um estudo transversal controlado, com hortifruticultores, durante o período de outubro de 2009 a outubro de 2010, a fim de caracterizar o uso de praguicidas, estabelecer o perfil sócio demográfico e analisar a atividade das colinesterases em trabalhadores rurais do sul do Brasil. Os dados foram obtidos de 173 trabalhadores e 179 controles. Um formulário estruturado foi aplicado obtendo informações sócio demográficas, conhecimento e práticas de trabalho relacionadas com o uso de praguicidas. Os valores de referência para colinesterases totais (ChEs) e butirilcolinesterase (BuChE) foram obtidos a partir da média da atividade enzimática do grupo controle. A idade média da população exposta foi de 40,0±11,2 anos. Os sinais/sintomas foram significativamente diferentes (p<0,05) entre a população exposta e não exposta. Quarenta trabalhadores (23,1%) apresentaram sinais/sintomas relacionados com a exposição aos praguicidas. O valor médio do grupo controle foi de 6,3 μmol/mL/min para o gênero masculino e 5,6 μmol/mL/min para o gênero feminino na ChEs; 2,4 μmol/mL/min para o gênero masculino e 2,0 μmol/mL/min para o gênero feminino na BuChE. Do total de trabalhadores (n=173), 08 (4,6%) apresentaram inibição elevada (>30%) das atividades das ChEs, e para BuChE nenhum trabalhador apresentou alta inibição (>50%). Dentre os fatores que poderiam estar envolvidos destacam-se o gênero, escolaridade, orientação para trabalhar com praguicidas, e...

show abstract

“…Indeed, leukemia, non-Hodgkin's lymphoma and other cancers (Richter and Chlamtac, 2002), neurologic pathologies, respiratory symptoms (Salameh et al, 2003) and hormonal and reproductive abnormalities have been associated with pesticide exposure, mostly in case-control and ecological studies. A variety of pesticides is used in greenhouses to maintain high crop yields.…”

Section: Introductionmentioning

confidence: 99%

Numerical Modelling and Experimental Measurements of Pesticides Dispersion in a Naturally Ventilated Greenhouse

Kittas¹,

Katsoulas²,

Tsiropoulos³

et al. 2008

Acta Hortic.

View full text Add to dashboard Cite

In the present study a commercial CFD code was used in order to investigate the dispersion of a pesticide inside an arch type tunnel greenhouse with continuous side vents. The greenhouse was cultivated with a tomato crop planted in double rows, which, during the period of measurements had a height of 1.5 m. In parallel, measurements were carried out in order to experimentally determine the decay rate of pesticide concentration. Air samples were continuously taken at seven points inside the greenhouse (six air pumps and one gas analyser). In the 3D numerical model calculations were done for several wind directions and wind speeds, using the experimental values as boundary conditions. The final solution for every case of wind direction and wind velocity was obtained, firstly by a converge solution under steady -state condition; and secondly by an unsteady one, where at the time which equals to zero the air volume in the experimental greenhouse was considered to contain a mixture consisting of air and the used pesticide. The simulation results that were in the same order of magnitude with the experimental values only during the first 5-6 minutes of unsteady solution and only qualitatively good agreement for the rest time, while the decay process was simulated. Even if different wind characteristics, as boundary conditions, were introduced in the CFD model every minute, the agreement remained in a qualitative level, showing that the concentration of the pesticide inside the greenhouse is a function not only of the greenhouse ventilation rate but also of the pesticide evaporation-volatilisation rate from the greenhouse crop, soil and cover surfaces. As the simulation model almost always underestimates the concentration levels inside the greenhouse, more investigation has to be carried out in order to obtain better agreement between measured and estimated values of pesticide concentration inside the greenhouse.

show abstract

Respiratory symptoms in children and exposure to pesticides

Cited by 107 publications

References 35 publications

Pesticides and respiratory symptoms among farmers

Pesticides and respiratory symptoms among farmers

Pesticide use and cholinesterase inhibition in small-scale agricultural workers in southern Brazil

Numerical Modelling and Experimental Measurements of Pesticides Dispersion in a Naturally Ventilated Greenhouse

Contact Info

Product

Resources

About