Respiratory Syncytial Virus Bronchiolitis in Children

Verger, Judy; Verger, Emily Elizabeth

doi:10.1016/j.ccell.2012.07.008

Cited by 6 publications

(7 citation statements)

References 116 publications

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“…For children with bronchiolitis, García et al [57][58][59] found three predictors of ICU admission: virus species (RSV vs. non-RSV), atelectasis/condensation, and co-infection. For children with RSV infection, Verger et al [60][61][62][63][64][65][66][67][68] identified several risk factors for ICU admission: immature lung development, prematurity, chronic lung disease, congenital heart disease (defined as congestive heart failure, cyanosis, or pulmonary hypertension), neuromuscular impairment, high nasal RSV viral load, surfactant protein A2 polymorphism, age < 6 weeks, neurological disease, cerebral palsy, male gender, lung consolidation, lethargy, grunting, high arterial PaCO 2 , an ED visit in the past week, presence of moderate to severe retractions, inadequate oral intake upon presentation in the ED, and mental retardation.…”

Section: Predicting Icu Admissionmentioning

confidence: 99%

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A systematic review of predictive modeling for bronchiolitis

Luo

Nkoy

Gesteland

et al. 2014

International Journal of Medical Informatics

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Purpose: Bronchiolitis is the most common cause of illness leading to hospitalization in young children. At present, many bronchiolitis management decisions are made subjectively, leading to significant practice variation among hospitals and physicians caring for children with bronchiolitis. To standardize care for bronchiolitis, researchers have proposed various models to predict the disease course to help determine a proper management plan. This paper reviews the existing state of the art of predictive modeling for bronchiolitis. Predictive modeling for respiratory syncytial virus (RSV) infection is covered whenever appropriate, as RSV accounts for about 70% of bronchiolitis cases.Methods: A systematic review was conducted through a PubMed search up to April 25, 2014. The literature on predictive modeling for bronchiolitis was retrieved using a comprehensive search query, which was developed through an iterative process.Search results were limited to human subjects, the English language, and children (birth-18 years). Results:The literature search returned 2,312 references in total. After manual review, 168 of these references were determined to be relevant and are discussed in this paper. We identify several limitations and open problems in predictive modeling for bronchiolitis, and provide some preliminary thoughts on how to address them, with the hope to stimulate future research in this domain. Conclusions:Many problems remain open in predictive modeling for bronchiolitis. Future studies will need to address them to achieve optimal predictive models.

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Section: Predicting Icu Admissionmentioning

confidence: 99%

“…The onset of RSV season is defined as the time when positive antigen tests are greater than 10% of those sampled [60].…”

Section: Predicting Community Rsv Activitymentioning

confidence: 99%

A systematic review of predictive modeling for bronchiolitis

Luo

Nkoy

Gesteland

et al. 2014

International Journal of Medical Informatics

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“…Key words: bronchiolitis, hospitalization, respiratory syncytial virus, poverty, crowded environment, breast feeding, masculine, premature nea, cardiopatías 13 , hipoxemia y exposición a humo de tabaco. [14][15][16][17][18][19][20][21][22][23] Por lo anterior consideramos importante conocer la prevalencia de bronquiolitis en la población que acudió al servicio de urgencias del Hospital de San José de Bogotá DC en el período 2013-2014, para determinar los factores de riesgo más frecuentes.…”

Section: Introductionunclassified

Bronquiolitis: Factores de riesgo en menores de dos años. Hospital de San José de Bogotá D.C. Colombia. 2013-2014

Preciado¹,

Castillo²,

Díaz³

et al. 2015

Repert. Med. Cir.

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ResumenObjetivo: determinar los factores de riesgo de bronquiolitis en menores de dos años que consultaron al servicio de urgencias del Hospital de San José de Bogotá DC entre 2013 y 2014. Materiales y métodos: estudio de tipo transversal mediante entrevistas a los acompañantes y análisis de las historias clínicas. Se registró la frecuencia de consultas en menores de dos años. Resultados: se reclutaron 127 pacientes con prevalencia de 2.8%. La mediana de edad fue 4 meses (RI 2-8 meses), en su mayoría hombres n: 74 (58.27%), los factores de riesgo fueron bajo peso al nacer n: 26 (20.47%), virus sincicial respiratorio (VSR) positivo n: 24 (18.9%) y prematuridad n: 20 (17.54%). Escolaridad de la madre (secundaria) n: 76 (59.84%), el 73.8% provenían de hogares de estrato bajo (1-2) factor frecuente en nuestra población, hermanos escolarizados n: 82 (64.57%) y exposición a humo de tabaco n: 22 (17.32%). Los meses de mayor consulta fueron marzo n: 34 (26.77%), abril n: 27 (21.26%) y julio n: 27 (21.26%). La mediana de estancia hospitalaria fue cinco días (RI 3 -7 días). Conclusiones: la etiología más frecuente fue el VSR; el palivizumab se utilizó en 7.09% de los pacientes. La prevención se basará en interrumpir la transmisión con técnicas de lavado y reducción de factores de riesgo ambientales, mientras se logra el desarrollo de la vacuna.Palabras clave: bronquiolitis, hospitalización, virus sincicial respiratorio, pobreza, aglomeración, lactancia materna, masculino, prematuro. Abreviaturas: VSR, virus sincicial respiratorio.Abstract Objective: to determine the risk factors associated to bronchiolitis in infants less than two years of age who consulted to the emergency ward at Hospital de San José, Bogotá DC between 2013 and 2014. Materials and Methods: a crosssectional study conducted by interviewing relatives and by clinical record analysis. The frequency of consultation of children less than two years of age was recorded. Results: 127 patients were recruited, prevalence 2.8%. Mean age was 4 months (IR 2 -8 months), mostly males n: 74 (58.27%), risk factors were, low weight at birth n: 26 (20.47%),

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“…La bronquiolitis aguda en niños es una enfermedad respiratoria infecciosa que constituye una causa frecuente de consulta en hospitales de primer y segundo nivel de atención 1,2 , sobre todo en invierno 1,3 . Esta enfermedad es causada generalmente por el virus sincicial respiratorio, que ocasiona inflamación y obstrucción de las vías respiratorias de pequeño calibre y da lugar a dificultad respiratoria, desde leve hasta severa 3 .…”

Section: Introductionunclassified

“…Esta enfermedad es causada generalmente por el virus sincicial respiratorio, que ocasiona inflamación y obstrucción de las vías respiratorias de pequeño calibre y da lugar a dificultad respiratoria, desde leve hasta severa 3 . Generalmente, el manejo va dirigido a dar apoyo respiratorio mientras se controla el proceso inflamatorio 1,2 .…”

Section: Introductionunclassified