Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999

Leader, Shelah; Kohlhase, Kimmie F.

doi:10.1097/00006454-200207000-00005

Cited by 249 publications

(190 citation statements)

References 7 publications

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“…[1][2][3][4][5][6][7] It is estimated that approximately two-thirds of all infants are infected with RSV within their first year of life and nearly all are infected by 2 years of age.…”

Section: R Espiratory Syncytial Virus (Rsv)mentioning

confidence: 99%

Medical Utilization Associated with Palivizumab Compliance in a Commercial and Managed Medicaid Health Plan

Diehl

Daw²,

Coley³

et al. 2010

JMCP

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BACKGROUND: Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections and hospitalization in infants. Palivizumab is currently the only available agent for prevention of RSV infection in highrisk infants. This high-cost injectable requires monthly dosing during the RSV season. Compliance with the injection schedule is important in the prevention of RSV infection and respiratory complications. Managed care organizations have an interest in the relationship between compliance with the palivizumab dosing schedule and respiratory-related medical outcomes such as emergency room (ER) visits, physician office visits, and hospitalizations.

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“…[1][2][3][4][5][6][7] It is estimated that approximately two-thirds of all infants are infected with RSV within their first year of life and nearly all are infected by 2 years of age.…”

Section: R Espiratory Syncytial Virus (Rsv)mentioning

confidence: 99%

Medical Utilization Associated with Palivizumab Compliance in a Commercial and Managed Medicaid Health Plan

Diehl

Daw²,

Coley³

et al. 2010

JMCP

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“…La bronquiolitis es una de las principales causas de hospitalización en los niños con menos de un año. La incidencia de ingresos por bronquiolitis por el virus respiratorio sincitial (55 casos/100.000 habitantes y año en el área de la Ribera ) superó al de otros patógenos de acuerdo con otros estudios 27 .…”

Section: Discussionunclassified

Ingresos hospitalarios por enfermedades infecciosas: incidencia desde 1999 hasta 2003 en un área sanitaria de la Comunidad Valenciana

Espejo

Dols

2007

Rev. Esp. Salud Publica

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RESUMENFundamento: La enfermedad infecciosa persiste en la actualidad como una de las principales causas de mortalidad y morbilidad. Su naturaleza dinámica justifica el estudio epidemiológico de las mismas. El objetivo del trabajo fue analizar la incidencia de enfermedades infecciosas que con mayor frecuencia condicionan el ingreso hospitalario.Métodos: Se realizó un estudio de las personas ingresadas entre los años 1999-2003 cuyo diagnóstico principal al alta hospitalaria se hubiera codificado, de acuerdo a la Clasificación Internacional de Enfermedades (CIE 9-MC), como enfermedad infecciosa en el Conjunto Mínimo Básico de Datos. Se seleccionaron 2.010 códigos de enfermedades infecciosas en actividad y se concentraron en 25 grupos adaptados al CIE 9-MC. La población diana fue la correspondiente a un area de la Comunidad Valenciana.Resultados: El 9,7% de los ingresos durante el periodo estudiado (8.585 registros) se debió a una enfermedad infecciosa. La media de edad de las personas afectadas fue 38 años, la mediana 37, la desviación típica 31 y el rango entre 0-102 años. Predominó el ingreso de varones (54,5%) sobre el de mujeres (45,5%). La tasa de incidencia de ingresos por enfermedades infecciosas fue de 728 casos/100.000 habitantes y año. La mayor tasa de ingreso se produjo en niños y ancianos. Los grupos de enfermedades con mayor número de ingresos fueron, en orden decreciente, las enfermedades infecciosas digestivas, respiratorias y genitourinarias. Conclusión:Los ingresos hospitalarios por enfermedades infecciosas alcanzaron la décima parte de los ingresos y 7 de cada 1.000 habitantes al año requirió ser hospitalizado con motivo de una patología infecciosa. Fue mayor la incidencia de las enfermedades intestinales, de aparato digestivo, respiratorio y genitourinario en la población infantil pero también, aunque en menor proporción, en los mayores de 65 años. BacKground:. Infectious diseases are still currently one of the leading causes of death and illness. Their dynamic nature justifies the epidemiological study thereof. This study is aimed at analyzing the incidence of infectious diseases most often conditioning hospital admissions. Methods:A study was conducted of those individuals admitted to hospital during the 1999-2003 period whose main diagnosis at admission to hospital had been encoded according to the International Disease Classification (ICD 9-CM) as an infectious disease in the Minimum Basic Data Set. A total of 2,010 active infectious disease codes were selected and were grouped into 25 groups as per the ICD 9-CM. The target population was that of one district in the Autonomous Community of Valencia.Results: A total of 9.7% of the admissions during the period under study (8,585 records) were due to an infectious disease. Those affected averaged 38 years of age, median age of 37, standard deviation 31 and the range of 1-102 years. The admissions of males (54.5%) prevailed over females (48.5%). The incidence rate of admissions due to infectious diseases was 728 cases / 100,000 inhabitants / yea...

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“…In the United States, RSV bronchiolitis has been reported to be the leading cause of hospital admissions among infants 35 and is the most frequently cited cause of hospitalization (ie, approximately 120,000 hospital admissions annually) due to serious lower respiratory tract disease in infants and young children. 22,31,[35][36][37][38] Reported hospitalization rates reported for infants range from 13 to 27.4 per 1000 births, with most hospitalizations reported for patients ,6 months of age, and particularly in infants aged 1 to 3 months.…”

Section: Rsv-related Hospitalization and Associated Costsmentioning

confidence: 99%

“…22,31,[35][36][37][38] Reported hospitalization rates reported for infants range from 13 to 27.4 per 1000 births, with most hospitalizations reported for patients ,6 months of age, and particularly in infants aged 1 to 3 months. [37][38][39][40][41][42] Among young children worldwide, RSV is the most common cause of LRTI and is a major cause of hospitalization for severe RSVrelated LRTI.…”

Section: Rsv-related Hospitalization and Associated Costsmentioning

confidence: 99%

Overview of respiratory syncytial virus disease in young children

Hoopes¹,

Kumar²

2012

PHMT

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Abstract:Respiratory tract illnesses associated with respiratory syncytial virus (RSV) were first reported more than 160 years ago and gained acceptance as a major respiratory pathogen in the late 1950s. Annual epidemics show a seasonal pattern typically beginning in the late fall and ending in early spring, averaging 5 months in length, and varying in time of onset, offset, and duration depending on geographic location. Manifestations of RSV illness primarily involve the upper respiratory tract but can spread to the lower airways and lead to bronchiolitis and/or pneumonia. Initial infection occurs in approximately two-thirds of children during the first year of life; nearly all children are infected at least once by 2 years of age. Reinfection is common throughout life, but initial illness during infancy generally presents with the most severe symptoms. Medical risk conditions that consistently predispose young children to serious lower respiratory tract infection (LRTI) include congenital heart disease, chronic lung disease, and premature birth. Serious LRTI due to RSV is the leading cause of hospitalization in infants and young children worldwide and annual mean hospital expenses have been estimated to exceed 1 billion dollars in the United States. Young children incur more inpatient and outpatient visits for RSV LRTI than for influenza. RSV has a greater impact than influenza on hospitalization in infants with respect to length of stay, severity/course of disease, and resultant needs for ancillary treatments. Unlike many other childhood illnesses, a vaccine is not currently available for preventing RSV disease.

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Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999

Abstract: RSV bronchiolitis was the leading cause of hospital admissions of infants younger than age 1 year for any reason between 1997 and 1999.

Cited by 249 publications

References 7 publications

Medical Utilization Associated with Palivizumab Compliance in a Commercial and Managed Medicaid Health Plan

Medical Utilization Associated with Palivizumab Compliance in a Commercial and Managed Medicaid Health Plan

Ingresos hospitalarios por enfermedades infecciosas: incidencia desde 1999 hasta 2003 en un área sanitaria de la Comunidad Valenciana

Overview of respiratory syncytial virus disease in young children

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