Respiratory syncytial virus infection—risk factors for hospital admission: a case‐control study

Nielsen, H. E.; Siersma, VD Volkert; Andersen, Stine Bang; Gahrn-Hansen, Bente; Mordhorst, Carl H.; Nørgaard‐Pedersen, Bent; Røder, Bent; Sørensen, T. I. A.; Temme, R; Bf, Vestergaard

doi:10.1111/j.1651-2227.2003.tb00502.x

Cited by 76 publications

(56 citation statements)

References 28 publications

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“…The lung capacity is reported to be lower in babies of mothers who smoke, especially during pregnancy (12,13). In a study conducted in Denmark, babies of mothers who smoked during pregnancy were reported to have more frequent episodes of bronchiolitis before the age of 2 (14). In this study, there was no correlation between smoking of the mothers during pregnancy and exposure to cigarette smoke and the frequency of emergency visits.…”

Section: Discussioncontrasting

confidence: 44%

Evaluating Predisposition Factors of Infants Presenting with Recurrent Bronchiolitis Episodes in İstanbul Bağcılar

Polat¹,

Erol²,

Yiğit³

et al. 2016

JAREM

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INTRODUCTIONThe American Academy of Pediatrics defines bronchiolitis as respiratory distress and wheezing that develops following the diagnosis of lower respiratory tract infection in children under two years of age. It is an inflammatory disease of the small airways that develops due to viral factors (1). Bronchiolitis is the most frequent cause of admissions to child emergency services and hospitalizations in the winter and spring months (2). While premature labor, underlying chronic pulmonary diseases such as bronchopulmonary dysplasia and cystic fibrosis or reactive airway disease, congenital heart disease, immunodeficiency and immunosuppression cases, and Down syndrome constitute the main risk factors, age of infants below six months, smoking exposure, atopy history, malnutrition, low birth weight, male gender, lower socioeconomic status, and crowded living conditions constitute additional risk factors (3,4). Although the duration of the disease is short and patients recover on their own in most cases, it requires hospitalization, especially in young children with high risk and patients with suppressed immunity, and it causes significant morbidity and mortality. While the mortality rate in bronchiolitis was found to be 0.5% in conducted studies, it was reported that this ratio exceeds 3% in patients with risk factors (5). Knowing the risk factors in acute bronchiolitis and taking steps in this direction bear great importance in terms of the health and development of infants. This study has been conducted to evaluate the predisposing factors in our patients who were treated for bronchiolitis. METHODSIn the study, face to face surveys were applied to parents of 220 children admitted to the emergency service and diagnosed with bronchiolitis between the dates of September 1, 2012 and December 31, 2012. It is a descriptive and cross-sectional study. The mothers and fathers participating in the application were given enlightening information about the purpose and importance of the study; thus, the study was based on their voluntary participation. The data were obtained from questionnaires applied by the researcher. The survey form contained questions regarding the number of rooms in the house the patient lives in and the number of people living at home, the ages of the parents, the smoking status, education, and occupations of the parents, and the average income of the family. The duration of the child's breastfeeding, whether or not the child had seizures, and the seasons in which the children were admitted to the hospital due to seizures were questioned. The height and weight of the children were measured. Evaluating Predisposition Factors of Infants Presenting with Recurrent Bronchiolitis Episodes in İstanbul Bağcılar ABSTRACTObjective: Bronchiolitis is the most common lower respiratory tract disease in infants. This study aimed to evaluate the relationship between predisposing factors and the number of applications to a hospital because of recurrent episodes of bronchiolitis.Methods: A questionnaire was admi...

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Section: Discussioncontrasting

confidence: 44%

Evaluating Predisposition Factors of Infants Presenting with Recurrent Bronchiolitis Episodes in İstanbul Bağcılar

Polat¹,

Erol²,

Yiğit³

et al. 2016

JAREM

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“…Infants experiencing viral seasons (e.g. RSV) during the first 6 months of life have a higher prevalence of asthma [19,20]. Animal studies have shown that early viral insults can affect the immune system with long lasting effects on immune and pulmonary function [21,22].…”

Section: Viruses and Asthmamentioning

confidence: 99%

Viral infections and asthma: an inflammatory interface?

et al. 2014

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Asthma is a chronic inflammatory disease of the airways in which the majority of patients respond to treatment with corticosteroids and b 2 -adrenoceptor agonists. Acute exacerbations of asthma substantially contribute to disease morbidity, mortality and healthcare costs, and are not restricted to patients who are not compliant with their treatment regimens. Given that respiratory viral infections are the principal cause of asthma exacerbations, this review article will explore the relationship between viral infections and asthma, and will put forward hypotheses as to why virus-induced exacerbations occur. Potential mechanisms that may explain why current therapeutics do not fully inhibit virus-induced exacerbations, for example, b 2 -adrenergic desensitisation and corticosteroid insensitivity, are explored, as well as which aspects of virus-induced inflammation are likely to be attenuated by current therapy. @ERSpublications Why do virus-induced asthma exacerbations occur? Mechanisms and interventions

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“…Six studies [14][15][16][17][18]21,23 estimated the risk of SAS. Meta-analysis gave an OR of 1.92 (95% CI 1.36 to 2.70).…”

Section: Siblings At School (Sas)mentioning

confidence: 99%

Palivizumab for immunoprophylaxis of respiratory syncitial virus (RSV) bronchiolitis in high-risk infants and young children: a systematic review and additional economic modelling of subgroup analyses

Wang¹,

Bayliss²,

Meads³

2011

Health Technol Assess

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume. How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. ii ii HTA NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service' . The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in the NHS, from the public and consumer groups and from professional bodies such as royal colleges and NHS trusts. These suggestions are carefully prioritised by panels of independent ex...

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Respiratory syncytial virus infection—risk factors for hospital admission: a case‐control study

Cited by 76 publications

References 28 publications

Evaluating Predisposition Factors of Infants Presenting with Recurrent Bronchiolitis Episodes in İstanbul Bağcılar

Evaluating Predisposition Factors of Infants Presenting with Recurrent Bronchiolitis Episodes in İstanbul Bağcılar

Viral infections and asthma: an inflammatory interface?

Palivizumab for immunoprophylaxis of respiratory syncitial virus (RSV) bronchiolitis in high-risk infants and young children: a systematic review and additional economic modelling of subgroup analyses

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