Respiratory viruses in HIV-infected patients with suspected respiratory opportunistic infection

Garbino, Jorge; Inoubli, Sarra; Mossdorf, Erik; Weber, Rainer; Tamm, Michael; Soccal, Paola M.; Aubert, John-David; Bridevaux, Pierre‐Olivier; Tapparel, Caroline; Kaiser, Laurent

doi:10.1097/qad.0b013e3282f470ac

Cited by 45 publications

(42 citation statements)

References 15 publications

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“…Respiratory viruses might contribute to pulmonary complications in HIV-infected patients, although information on the causes, risk factors and outcomes of respiratory viral infection in these patients is very scarce [124][125][126]. Moreover, the respective role of each agent could vary according to the population and the season studied [124,127,128].…”

Section: Viral Infectionsmentioning

confidence: 99%

“…Moreover, the respective role of each agent could vary according to the population and the season studied [124,127,128]. Influenza is a common cause of respiratory illness in adults with HIV, although HAART seems to have reduced the number of patients treated for influenza in hospital [124,129]. People with HIV are usually considered to be at increased risk from serious influenza-related complications, mostly based on studies carried out in the pre-HAART era [130].…”

Section: Viral Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary infections in HIV-infected patients: an update in the 21st century

Benito¹,

Moreno²,

Miró³

et al. 2011

Eur Respir J

176

216

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From the first descriptions of HIV/AIDS, the lung has been the site most frequently affected by the disease. Most patients develop a pulmonary complication during the history of HIV infection, mainly of infectious aetiology.Important changes in the epidemiology of HIV-related pulmonary infections have occurred. Overall, prescription of Pneumocystis jirovecii prophylaxis and the introduction of highly active antiretroviral therapy (HAART) are the main causes.Currently, the most frequent diagnosis in developed countries is bacterial pneumonia, especially pneumococcal pneumonia, the second most frequent cause is Pneumocystis pneumonia and the third is tuberculosis. However, in Africa, tuberculosis could be the most common pulmonary complication of HIV.Pulmonary infections remain one of the most important causes of morbidity and mortality in these patients, and the first cause of hospital admission in the HAART era. Achieving an aetiological diagnosis of pulmonary infection in these patients is important due to its prognostic consequences.

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Section: Viral Infectionsmentioning

confidence: 99%

Section: Viral Infectionsmentioning

confidence: 99%

Pulmonary infections in HIV-infected patients: an update in the 21st century

Benito¹,

Moreno²,

Miró³

et al. 2011

Eur Respir J

176

216

View full text Add to dashboard Cite

show abstract

“…In addition, the association with lower respiratory tract symptoms, and in particular, wheezing, has led to speculation of its role in lower respiratory tract illness. One case of an HIV-infected patient with HBoV DNA detected in a bronchoalveolar lavage specimen has been described, supporting its role in lower respiratory tract illness (72).…”

Section: Human Bocavirusmentioning

confidence: 99%

Human Metapneumovirus and Human Bocavirus in Children

Milder

Arnold

2009

Pediatr Res

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Several new viruses have recently been described in children, including human metapneumovirus (hMPV) and human bocavirus (HBoV). hMPV has been established as a common cause of upper and lower respiratory tract infections in children, often second only to respiratory syncytial virus as a cause of bronchiolitis in infants. Diagnostic tools have been developed for the clinician and effective treatment and prevention strategies are being investigated. HBoV was more recently identified. Although it was initially identified in the airway of children, high rates of codetection of other viral pathogens and detection of the virus in the stool have raised questions about the true role of HBoV as a cause of respiratory infections. A focus on epidemiology, pathogenesis, clinical features, and diagnostic techniques for hMPV and HBoV is presented.

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“…True pathogenicity of HBoV as a sole pathogen in respiratory tract infections has been largely obscured by the fact that HBoV is frequently found simultaneously with other respiratory viruses (16). While infections caused by HBoV are frequent, severe cases are rare in immunocompetent (17,19,21) and immunocompromised (10,14,18) patients. Until now, visualization of HBoV virions by EM was described only twice, in patients with high viral loads (5, 7).…”

Section: Case Reportmentioning

confidence: 99%