Response calibration in neuroblastoma cultures over multielectrode array

Cuadra, J. M.; Sánchez, José Luis Guzmán; Santos, Daniel de Matos Luna dos; Lorente, V.; Vicente, José Manuel Ferrández; Paz, Félix de la; Fernández, Eduardo

doi:10.1016/j.neucom.2011.04.038

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2013

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“…Furthermore, this multi-analysis approach is also fully compatible with the monitoring of cells cultures, leading to the realization of multi electrode arrays (MEA) and metal-oxide-semiconductor field effect transistor (MOSFET) based integrated circuits. Both technologies were used for the measurement of cellular electrochemical parameters [7][8][9] and of neuronal activities [10,11]. Nevertheless, compared to the MEA one, the FET technology was shown to be more adapted for such application.…”

Section: Introductionmentioning

confidence: 99%

Parallel detection in liquid phase of N-channel MOSFET/ChemFET microdevices using saturation mode

Larramendy

Mathieu

Charlot

et al. 2013

Sensors and Actuators B: Chemical

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MOSFET and ChemFET are currently being used in many types of applications for the measurement of electrochemical potential and pH in liquid phase. This paper presents the realization of an analysis micro device including the micro sensor chip, the on-board electronic and the associated fluidics. The whole micro system can be easily transported, used for cellular cultures monitoring or chemical test thanks to a specific electronic interface. Using the transistor saturation mode, this interface enables both static and dynamic measurements for ChemFET and MOSFET-based devices, reducing electrical measurement interferences (up to 50dB) coming from the liquid phase.

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