During their lifecycle, wind turbines can be subjected to multiple hazard loads, such as high-intensity wind, earthquake, wave, and mechanical unbalance. Excessive vibrations, due to these loads, can have detrimental effects on energy production, structural lifecycle, and the initial cost of wind turbines. Vibration control by various means, such as passive, active, and semi-active control systems provide crucial solutions to these issues. We developed a novel control theory that enables semi-active controller tuning under the complex structural behavior and inherent system nonlinearity. The proposed theory enables the evaluation of semi-active controllers’ performance of multi-degrees-of-freedom systems, without the need for time-consuming simulations. A wide range of controllers can be tested in a fraction of a second, and their parameters can be tuned to achieve system-level performance for different optimization objectives.