Identify the sources of resistance to Cercospora leaf spot and Fusarium wilt diseases in Cotton under natural field conditions with artificial inoculation at Regional Agricultural Research Station, Warangal of the Telangana State in India. The experimental material consisted of Fifty two cotton germplasms and 13 Bt cotton hybrids with a check. They were tested against Cercospora leaf spot and Fusarium wilt diseases during Kharif 2016. Out of 52 cotton germplasms,14 entries viz.,HYPS-152,H-1250,SA-434,KH-2244N,KH-134,MRK-38,LH-2170,AKH-2822,LH-900,JK-2764,NH-615, GBHU-164,RAH-100 and HOC-5 were found resistant to Cercospora leaf spot and nine entries namely MCU-13, HYPS-152, H-1250, RAH-4, RCH-2, JK-2764, CCH1071, SCS-101, CCH-11 were found resistant to Fusarium wilt disease.Out of screened 13 Bt cotton hybrids, one entry Ankur-3224 was found resistant to Cercospora leaf spot disease and three entries namely First class, Ankur-3224 and RCH-812 were found moderately resistant to Fusarium wilt disease.