Response of hydrogenase enzymes (ALDH and ADH) in &amp;lt;i&amp;gt;Trapa natans&amp;lt;/i&amp;gt; under physiological stress

Kaur, Neha Pathania-Gagandeep; Singh, Jogendra; Vyas, Ashish Kumar; Kumar, Manoj

doi:10.4236/abb.2012.34043

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…17,18) Cytochrome P450 (CYP)2E1 Enzyme Activity Assay CYP2E1 enzyme activity was determined by the method described previously. 19) In brief, the livers were perfused with ice-cold 0.15 M KCl and homogenised in a homogeniser with 4 volumes (w/v) of 10 mM Tris-HCl (pH 7.4) containing 0.15 M KCl, 0.1 mM ethylenediamine tetraacetic acid (EDTA), 1.0 mM dithiothreitol and 0.01 mM phenylmethylsulphonyl fluoride.…”

Section: Alcohol and Acetaldehyde Concentrations In Plasmamentioning

confidence: 99%

Retraction: Asiatic Acid from Potentilla chinensis Attenuate Ethanol-Induced Hepatic Injury via Suppression of Oxidative Stress and Kupffer Cell Activation

Wei

Huang

et al. 2013

Biological & Pharmaceutical Bulletin

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This study examined the effect of Asiatic acid from Potentilla chinensis (AAPC) on chronic ethanolinduced hepatic injury. Rats underwent intragastric administration of ethanol (5.0-9.0 g/kg) once a day for 12 weeks. A subset of rats were also intragastrically treated with AAPC (2, 4 or 8 mg/kg) once a day. In the end, AAPC treatment significantly protected against ethanol-induced liver injury, as evidenced by the decrease in serum alanine and aspartate aminotransferases levels and the attenuation of histopathological changes in rats. Additionally, AAPC significantly decreased blood alcohol and acetaldehyde concentrations by enhancing alcohol dehydrogenase and aldehyde dehydrogenase activities. Mechanistically, studies showed that AAPC remarkably alleviated the formations of malondialdehyde and myeloperoxidase, restored impaired antioxidants, including superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase, and inhibited cytochrome P450 (CYP)2E1 activity. Moreover, the over-expression of cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), the elevated plasma endotoxin level and the up-regulated Toll-like receptor 4 (TLR4), CD14 and myeloid differentiation factor 88 (MyD88) as well as nuclear factor-κB were also suppressed by AAPC in ethanol-intoxicated rats. In conclusion, the protective effect of AAPC on ethanol-induced hepatotoxicity was mainly due to its ability to attenuate oxidative stress and inhibit Kupffer cell activation by decreasing the level of plasma endotoxin and the expression of TLR4, CD14 and MyD88.

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Section: Alcohol and Acetaldehyde Concentrations In Plasmamentioning

confidence: 99%

Retraction: Asiatic Acid from Potentilla chinensis Attenuate Ethanol-Induced Hepatic Injury via Suppression of Oxidative Stress and Kupffer Cell Activation

Wei

Huang

et al. 2013

Biological & Pharmaceutical Bulletin

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Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats

Huang

Zhang

et al. 2013

Toxicology Letters

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Long-Term Changes in and Conservation Guidelines for Water Caltrop (Trapa natans L.) in Two Reservoirs in Poland

Jusik

Bryl

Staniszewski

et al. 2023

Water

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Climate change, worsening freshwater quality, and anthropogenic factors have caused water caltrop to lose approximately 80% of its habitat in Poland since the early 1980s. The presence of this plant species has substantially changed since the end of the 19th century. Our aim in this study was to examine the habitat and conservation status of Trapa natans in the Szumirad reservoir and Nowokuźnicki pond reserve in Poland and to indicate sources of potential hazards for the analyzed population. To achieve this aim, we spatially analyzed the changes in the total reservoir area, dynamics of species population, physico-chemical parameters of water, and climatic data. For the Szumirad reservoir, we observed substantial changes in water caltrop quantity and condition. For the Nowokuźnicki pond reserve, we found a serious threat to the Trapa habitat posed by the developing Nupharo–Nymphaeetum albae association, which is a strong competitor of nymphaeids. The obtained results indicated that surface waters localized in protected areas might play an important role in maintaining the population of water caltrop. On the basis of our analyses of selected populations, we emphasize that present protection procedures should be supplemented with the active protection of the species.

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Response of hydrogenase enzymes (ALDH and ADH) in <i>Trapa natans</i> under physiological stress

Cited by 3 publications

References 10 publications

Retraction: Asiatic Acid from <i>Potentilla chinensis</i> Attenuate Ethanol-Induced Hepatic Injury <i>via</i> Suppression of Oxidative Stress and Kupffer Cell Activation

Retraction: Asiatic Acid from <i>Potentilla chinensis</i> Attenuate Ethanol-Induced Hepatic Injury <i>via</i> Suppression of Oxidative Stress and Kupffer Cell Activation

Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats

Long-Term Changes in and Conservation Guidelines for Water Caltrop (Trapa natans L.) in Two Reservoirs in Poland

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