Abstract:The influence of cell-free extract of mouse fibrosarcoma and normal fibroblast on the early development and organogenesis of mouse embryos, and on the histology of non-pregnant and pregnant uteri was studied in vivo. Both normal and tumour cell extracts inhibited normal mouse embryogenesis. However, the effects of tumour extract on mouse embryogenesis was far more drastic and significant. Despite such changes, no basic alteration of the morphology of the embryonic cells was seen. Observations on the uterine hi… Show more
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