Response of pharyngeal gonorrhoea to single dose penicillin treatment.

Sulaiman, M. Z. C.; Bates, Clark; Bittiner, J. B.; Dixon, C A; Slack, R. C. B.

doi:10.1136/sti.63.2.92

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…37, 38 The data on screening for women for extra-genital infection is mixed. Studies conducted in the 1970s and 1980s found that among women with genital tract infections with N. gonorrhoeae, approximately 10–25% had concurrent pharyngeal gonorrhea, 33–36, 40–42 and nearly 40% had concurrent rectal infection. 42 However, isolated extra-genital infections (without concurrent cervical infection) in women were not common in those studies, and the U.S. CDC does not recommend extra-genital screening for women.…”

Section: Screening and Diagnosismentioning

confidence: 99%

Control of Neisseria gonorrhoeae in the Era of Evolving Antimicrobial Resistance

Barbee

Dombrowski

2013

Infectious Disease Clinics of North America

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Neisseria gonorrhoeae has developed resistance to all previous first-line antimicrobial therapies recommended by the United States’ Centers for Disease Control and Prevention over the past 75 years. Now the cephalosporins, the last available antibiotic class that is sufficiently effective, economical, and feasibly delivered in the outpatient setting are also threatened by evolving resistance. Screening for asymptomatic gonorrhea in women and men who have sex with men, treating with a dual antibiotic regimen, ensuring effective partner therapy and remaining vigilant for treatment failures constitute critical activities for clinicians in responding to evolving antimicrobial resistance. In this article, we will review the epidemiology, antimicrobial resistance history, current screening and treatment guidelines, and future treatment options for gonorrhea.

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Section: Screening and Diagnosismentioning

confidence: 99%

Control of Neisseria gonorrhoeae in the Era of Evolving Antimicrobial Resistance

Barbee

Dombrowski

2013

Infectious Disease Clinics of North America

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The diagnosis of oropharyngeal gonorrhoea.

Barlow¹

1997

Sexually Transmitted Infections

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Much of the published work on gonococcal infection of the throat dates from the seventies and early eighties, a period during which the incidence of gonorrhoea in the Western world was significantly greater than today. Epidemiology There is general agreement that oropharyngeal infection occurs most frequently in homosexual men, followed by women and heterosexual men. The table gives comparative prevalences from four studies of patients with gonorrhoea.Weisner et al4 found the oropharyngeal isolation rate of neisseria species from his population was: N meningitidis 17.2%; N gonorrhoeae 5.6% and N lactamica 1 9%.Young and Bain5 noted that, of gram-negative diplococci cultured, 74.2% were N meningitidis, 20.3% N gonorrhoeae and 3.7% N lactamica. DiagnosisNo standard method has been agreed for sampling the oropharynx and it is therefore difficult to compare the prevalence of oropharyngeal gonococcal infection between different studies. In their pioneering article in 1973, Bro-Jorgensen and Jensen were not only the first to recommend routine cultures from the oropharynx of patients with gonorrhoea, but described a thorough technique worth following: ". . . avoiding wetting the swab with saliva, swabs were rubbed against the surface of the tonsils, inserted into the crypts and the spaces between the palatine arches and the tonsils and finally rolled over the posterior pharynx".2 There are no published studies on the value or otherwise of multiple sampling from the oropharynx, as there are for other sites.Microscopy of samples from the oropharynx is unhelpful in the diagnosis or exclusion of gonorrhoea because of the presence of other neisseria species. Laboratory culture is therefore necessary with further differentiation between different neisseriae, simple carbohydrate utilisation tests having been largely superseded by commercial immunological tests based on monoclonal antibodies and, if necessary, biochemical tests. Recent work by Comparative prevalences of oropharyngeal gonorrhoea Source (n) Women, % +ve Het men, % +ve Hls men, % +ve Weisner' (2224) 10-3% 3-2% 20-9%

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Response of pharyngeal gonorrhoea to single dose penicillin treatment.

Cited by 2 publications

References 15 publications

Control of Neisseria gonorrhoeae in the Era of Evolving Antimicrobial Resistance

Control of Neisseria gonorrhoeae in the Era of Evolving Antimicrobial Resistance

The diagnosis of oropharyngeal gonorrhoea.

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