Charge-coupled device (CCD) is widely used as a detector of vacuum spectrometers in fusion devices. Recently, a deuterium plasma experiment has been initiated in Large Helical Device (LHD). Totally 3.7´10 18 neutrons have been yielded with energies of 2.45 MeV (D-D) and 14.1 MeV (D-T) during the deuterium experiment over four months. Meanwhile, g-rays are radiated from plasma facing components and laboratory structural materials in a wide energy range, i.e., 0.01-12.0 MeV, through the neutron capture. It is well known that these neutrons and g-rays bring serious problems to the CCD system. Then, several CCDs of vacuum ultraviolet (VUV) / extreme ultraviolet (EUV) / X-ray spectrometers installed at different locations on LHD for measurements of spectra and spatial profiles of impurity emission lines are examined to study the effect of neutrons and g-rays. An additional CCD placed in a special shielding box made of 10 cm thick polyethylene contained 10% boron and 1.5 cm thick lead is also used for the detailed analysis. As a result, it is found that the CCD has no damage in the present neutron yield of LHD, while the background noise integrated for all pixels of CCD largely increases, i.e., 1-3 ´ 10 8 counts/s. The data analysis of CCD in the shielding box shows that the background noise caused by the g-ray is smaller than that caused by the neutron, i.e., 41% from g-rays and 59% from neutrons. It is also found that the noise can be partly removed by an accumulation of CCD frames or software programming.