Buckwheat (Fagopyrum esculentum Moench) is a prominent crop in today’s agriculture. However, information about its behavior at different doses of NPK fertilization is scarce. The aim of this work was to determine the ideal fertilizer dose for the buckwheat cultivar IPR 91 Baili by establishing the dose-response curve. Two experiments were carried out (greenhouse and in the field). The treatments consisted of different doses of NPK (0, 100, 200, 300, 400 and 500 kg ha-1). After the crop cycle, productivity was obtained. There was a statistical difference between the treatments and the control, in both experiments. The lowest yields were obtained in the controls, 2,301.156 and 2,262.500 kg ha-1, and the highest 4,052.023 and 4,027.778 kg ha-1 at the dose of 500 kg ha-1, in the greenhouse and in the field, respectively. There was no statistical difference between the NPK doses for the yield obtained. The rural producer must use the lowest dose (100 kg ha-1). Future experiments are needed to evaluate the culture response to doses below 100 kg ha-1.