Responses of Reticulospinal Neurons in the Lamprey to Lateral Turns

Karayannidou, Anastasia; Zelenin, Pavel V.; Orlovsky, G. N.; Deliagina, T. G.

doi:10.1152/jn.00912.2006

Cited by 12 publications

(28 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They were proposed to result from additional excitation of populations of RS cells on one side, allowing the body of the animal to change direction. This has been demonstrated experimentally (McClellan and Hagevik, 1997;Karayannidou et al, 2007).…”

Section: Functional Significancementioning

confidence: 70%

The Transformation of a Unilateral Locomotor Command into a Symmetrical Bilateral Activation in the Brainstem

Brocard¹,

Ryczko²,

Fénelon³

et al. 2010

J. Neurosci.

View full text Add to dashboard Cite

Section: Functional Significancementioning

confidence: 70%

The Transformation of a Unilateral Locomotor Command into a Symmetrical Bilateral Activation in the Brainstem

Brocard¹,

Ryczko²,

Fénelon³

et al. 2010

J. Neurosci.

View full text Add to dashboard Cite

“…Transition from one position to another lasted 0.5-1 s, and each position was maintained for 1-4 s. With each type of rotation, individual animals were tested at least three times. The neurons responding differently to rotation in opposite directions (at least in 1 plane) were considered as involved in the control of body orientation Pavlova and Deliagina 2002;Karayannidou et al 2007;Zelenin et al 2007). …”

Section: Methodsmentioning

confidence: 99%

“…To reveal RS neurons related to the postural control system (these neurons are driven by vestibular input) Pavlova and Deliagina 2002;Karayannidou et al 2007) five animals were subjected to natural vestibular stimulation caused by rotation of the animal in different planes (see MATERIALS AND METHODS and Fig. 7A).…”

Section: Revealing Neurons Participating In Postural Controlmentioning

confidence: 99%

See 1 more Smart Citation

Reticulospinal neurons controlling forward and backward swimming in the lamprey

Zelenin

2011

Journal of Neurophysiology

Self Cite

View full text Add to dashboard Cite

Zelenin PV. Reticulospinal neurons controlling forward and backward swimming in the lamprey. J Neurophysiol 105: 1361-1371, 2011. First published January, 19, 2011 doi:10.1152 doi:10. /jn.00887.2010brates are capable of two forms of locomotion, forward and backward, strongly differing in the patterns of motor coordination. Basic mechanisms generating these patterns are located in the spinal cord; they are activated and regulated by supraspinal commands. In the lamprey, these commands are transmitted by reticulospinal (RS) neurons. The aim of this study was to reveal groups of RS neurons controlling different aspects of forward (FS) and backward (BS) swimming in the lamprey. Activity of individual larger RS neurons in intact lampreys was recorded during FS and BS by chronically implanted electrodes. It was found that among the neurons activated during locomotion, 27% were active only during FS, 3% only during BS, and 70% during both FS and BS. In a portion of RS neurons, their mean firing frequency was correlated with frequency of body undulations during FS (8%), during BS (34%), or during both FS and BS (22%), suggesting their involvement in control of locomotion intensity. RS activity was phasically modulated by the locomotor rhythm during FS (20% of neurons), during BS (29%), or during both FS and BS (16%). The majority of RS neurons responding to vestibular stimulation (and presumably involved in control of body orientation) were active mainly during FS. This explains the absence of stabilization of the body orientation observed during BS. We discuss possible functions of different groups of RS neurons, i.e., activation of the spinal locomotor CPG, inversion of the direction of propagation of locomotor waves, and postural control. supraspinal commands; reticulospinal system; backward locomotion; forward locomotion; posture

show abstract

“…1B), RS neurons respond to rotation in different planes in both the whole animal and in vitro preparation (Deliagina et al, 1992a;Deliagina and Fagerstedt, 2000). In each of the main planes (pitch, roll, yaw), there are two antagonistic groups of RS neurons responding to rotation in opposite directions (Deliagina and Fagerstedt, 2000;Deliagina et al, 1992aDeliagina et al, ,2006aKarayannidou et al, 2005;Pavlova and Deliagina, 2002). These groups are shown in Figs.…”

Section: Postural Control In Lampreymentioning

confidence: 99%

Spinal and supraspinal postural networks

Deliagina¹,

Beloozerova²,

Zelenin³

et al. 2008

Brain Research Reviews

116

View full text Add to dashboard Cite

Different species maintain a particular body orientation in space (upright in humans, dorsal-side-up in quadrupeds, fish and lamprey) due to the activity of a closed-loop postural control system. We will discuss operation of spinal and supraspinal postural networks studied in a lower vertebrate (lamprey) and in two mammals (rabbit and cat).In the lamprey, the postural control system is driven by vestibular input. The key role in the postural network belongs to the reticulospinal (RS) neurons. Due to vestibular input, deviation from the stabilized body orientation in any (roll, pitch, yaw) plane leads to generation of RS commands, which are sent to the spinal cord and cause postural correction. For each of the planes, there are two groups of RS neurons responding to rotation in the opposite directions; they cause a turn opposite to the initial one. The command transmitted by an individual RS neuron causes the motor response, which contributes to the correction of posture. In each plane, the postural system stabilizes the orientation at which the antagonistic vestibular reflexes compensate for each other. Thus, in lamprey the supraspinal networks play a crucial role in stabilization of body orientation, and the function of the spinal networks is transformation of supraspinal commands into the motor pattern of postural corrections.In terrestrial quadrupeds, the postural system stabilizing the trunk orientation in the transversal plane was analyzed. It consists of two relatively independent sub-systems stabilizing orientation of the anterior and posterior parts of the trunk. They are driven by somatosensory input from limb mechanoreceptors. Each sub-system consists of two closed-loop mechanisms -spinal and spinosupraspinal. Operation of the supraspinal networks was studied by recording the posture-related activity of corticospinal neurons. The postural capacity of spinal networks was evaluated in animals with lesions to the spinal cord. Relative contribution of spinal and supraspinal mechanisms to the stabilization of trunk orientation is discussed.

show abstract

Responses of Reticulospinal Neurons in the Lamprey to Lateral Turns

Cited by 12 publications

References 38 publications

The Transformation of a Unilateral Locomotor Command into a Symmetrical Bilateral Activation in the Brainstem

The Transformation of a Unilateral Locomotor Command into a Symmetrical Bilateral Activation in the Brainstem

Reticulospinal neurons controlling forward and backward swimming in the lamprey

Spinal and supraspinal postural networks

Contact Info

Product

Resources

About