The tomato (Solanum lycopersicum) is one of the main vegetables grown in Sinaloa. This crop is affected by pest insects, such as the white fly (Bemisia tabaci). The objective was to evaluate the effect of different doses of neem-based biorational insecticide on the population density of whiteflies. A completely randomized design was established to evaluate the population density of whitefly adults. The treatments evaluated were different doses of neem leaf extracts (NLE): (T1) control, (T2) 200 g NLE•L-1, (T3) 300 g NLE•L-1, (T4) 400 g NLE•L-1 and (T5) 500 g NLE•L-1. An analysis of covariance was applied to the data obtained and the difference between the means was evaluated using the Tukey test with an α=0.05. Neem extracts had an effect on population density (p≤0.05), by reducing the population as the concentration of the extracts increased. T5 presented the highest reduction with 43.56%±1.6, while T4 presented a reduction of 39.27%±1.7, compared to the control. However, the application of T5 causes damage to the plant, so it can be considered that T4 is more suitable for its application. Therefore, neem extracts had an effect in controlling the whitefly population.