Responsive Polymeric Nanotherapeutics

Pamfil, Daniela; Vasile, Cornelia

doi:10.1016/b978-0-12-813932-5.00002-9

Cited by 8 publications

(4 citation statements)

References 283 publications

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“…Stimuli responsive nanocomposites/nanocoatings prepared using “stimuli-responsive, “smart,” “intelligent” or “environmentally sensitive” polymers [ 282 , 283 , 284 , 285 ]. These polymers respond to environmental changes by changing their conformation, solubility, hydrophilic/hydrophobic balance, reaction rate, swelling and release behaviour (for hydrogels) and molecular recognition.…”

Section: Applicationsmentioning

confidence: 99%

Polymeric Nanocomposites and Nanocoatings for Food Packaging: A Review

Vasile

2018

Materials

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198

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Special properties of the polymeric nanomaterials (nanoscale size, large surface area to mass ratio and high reactivity individualize them in food packaging materials. They can be processed in precisely engineered materials with multifunctional and bioactive activity. This review offers a general view on polymeric nanocomposites and nanocoatings including classification, preparation methods, properties and short methodology of characterization, applications, selected types of them used in food packaging field and their antimicrobial, antioxidant, biological, biocatalyst and so forth, functions.

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Section: Applicationsmentioning

confidence: 99%

Polymeric Nanocomposites and Nanocoatings for Food Packaging: A Review

Vasile

2018

Materials

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198

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“…Such nanostrategies hold potential for generating effective clinical outcomes in epilepsy patients. 12,13 These advancements in nanotechnology-based approaches for epilepsy management offer novel ways to address the challenges associated with traditional drug delivery systems. Nanotherapeutics have the potential to improve treatment efficacy, reduce side effects, and provide sitespecific drug delivery for enhanced clinical outcomes.…”

Section: Epilepsymentioning

confidence: 99%

Recent advances in nanotherapeutics for epilepsy and neurodegenerative diseases

Kuchik,

Doke,

Bhor

et al. 2023

JPBS

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This review focuses on the potential of nanotherapeutics in the diagnosis and treatment of neuronal abnormal conditions particularly epilepsy, alzheimer's disease (AD), and Parkinson's disease (PD). The advancements in nanotechnology have paved the way for the development of nanocarrier systems that can target the underlying pathogenesis of these diseases. The study aimed to explore the efficacy of nanosystems in treating epilepsy, AD, and PD by analyzing relevant articles from databases such as Medline, PubMed and the national library of medicine. The review discusses the targeted delivery of active therapeutics to the central nervous system, with a focus on modulating neuronal and endothelial cell activity. It highlights various nanotherapeutic approaches, including pH-responsive nanomaterial-based therapeutics, nano-bioelectronic-implantable transient electronic devices, and electro-responsive nanosystems for the treatment of epilepsy. Additionally, the efficacy of nanodrug delivery systems loaded with curcumin, monoclonal anti-tau antibody-coated gold nanoparticles, Polyethylene Glycolpolylactide-Polyglycolide (PEG-PLGA) nanoparticles loaded with lactoferrin, dopamine-conjugated Albumin/PLGA nanosystems, and curcumin-loaded T807/RPCNP nanoparticles against neurodegeneration is discussed. The findings of this review provide valuable insights into the implications and challenges of nanotherapeutics in the field of neurological diseases. Neurologists and clinicians can benefit from this knowledge to better understand the potential applications of nanotherapeutics in the diagnosis and treatment of these conditions.

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“…Stimuli-responsive DDSs (Table 2) can respond to any kind of physical, chemical, or biological changes, which leads to provision of drugs at the right time in target site [88][89][90]. These triggers are summarized in Figure 5.…”

Section: Smart Systemsmentioning

confidence: 99%

Electrospun Fibers: Versatile Approaches for Controlled Release Applications

Afshar

Abdorashidi

Dorkoosh

et al. 2022

International Journal of Polymer Science

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Electrospinning has been one of the most attractive methods of fiber fabrication in the last century. A lot of studies have been conducted, especially in tissue engineering and drug delivery using electrospun fibers. Loading many different drugs and bioactive agents on or within these fibers potentiates the efficacy of such systems; however, there are still no commercial products with this technology available in the market. Various methods have been developed to improve the mechanical and physicochemical behavior of structures toward more controllable delivery systems in terms of time, place, or quantity of release. In this study, most frequent methods used for the fabrication of controlled release electrospun fibers have been reviewed. Although there are a lot of achievements in the fabrication of controlled release fibers, there are still many challenges to be solved to reach a qualified, reproducible system applicable in the pharmaceutical industry.

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Responsive Polymeric Nanotherapeutics

Cited by 8 publications

References 283 publications

Polymeric Nanocomposites and Nanocoatings for Food Packaging: A Review

Polymeric Nanocomposites and Nanocoatings for Food Packaging: A Review

Recent advances in nanotherapeutics for epilepsy and neurodegenerative diseases

Electrospun Fibers: Versatile Approaches for Controlled Release Applications

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