2024
DOI: 10.1111/aos.16768
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Responsiveness of anti‐VEGF treatment for polypoidal choroidal vasculopathy based on aqueous humour proteomics: A preliminary study

Yuelin Wang,
Dongjun Xing,
Jialiang Duan
et al.

Abstract: ObjectivesPatients with polypoidal choroidal vasculopathy (PCV) exhibit variability in response to anti‐VEGF therapy. This study aimed to analyse the aqueous humour proteomic profiles of PCV patients and provide preliminary insights for the identification of biomarkers associated with anti‐VEGF drug responsiveness.MethodsPCV patients who were treatment‐naïve or untreated for more than 3 months were prospectively recruited from two hospitals in Beijing and Tianjin. Based on the relative changes in central macul… Show more

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