Resting-state and vocabulary tasks distinctively inform on age-related differences in the functional brain connectome

Ferré, Perrine; Benhajali, Yassine; Steffener, Jason; Stern, Yaakov; Joanette, Yves; Bellec, Pierre

doi:10.1080/23273798.2019.1608072

Cited by 10 publications

(3 citation statements)

References 159 publications

(184 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Taken together, these data imply a likely inverse coupling between resting and task-related functional networks underlying vocabulary knowledge, in line with the recent functional MRI results of increased functional connectivity during task but decreased functional connectivity during resting-state for vocabulary-sensitive brain networks (Ferré et al, 2019).…”

Section: Discussionsupporting

confidence: 87%

The development of brain rhythms at rest and its impact on vocabulary acquisition

Meng

Sun

et al. 2021

Developmental Science

View full text Add to dashboard Cite

A long-standing question in developmental science is how the neurodevelopment of the brain influences cognitive functions. Here, we examined the developmental change of resting EEG power and its links to vocabulary acquisition in school-age children. We further explored what mechanisms may mediate the relation between brain rhythm maturation and vocabulary knowledge. Eyes-opened resting-state EEG data were recorded from 53 typically-developing Chinese children every 2 years between the ages of 7 and 11. Our results showed first that delta, theta, and gamma power decreased over time, whereas alpha and beta power increased over time. Second, after controlling for general cognitive abilities, age, home literacy environment, and phonological skills, theta decreases explained 6.9% and 14.4% of unique variance in expressive vocabulary at ages 9 and 11, respectively. We also found that beta increase from age 7 to 9 significantly predicted receptive vocabulary at age 11. Finally, theta decrease predicted expressive vocabulary through the effects of phoneme deletion at age 9 and tone discrimination at age 11. These results substantiate the important role of brain oscillations at rest, especially theta rhythm, in language development. The developmental change of brain rhythms could serve as sensitive biomarkers for vocabulary development in school-age children, which would be of great value in identifying children at risk of language impairment.

show abstract

Section: Discussionsupporting

confidence: 87%

The development of brain rhythms at rest and its impact on vocabulary acquisition

Meng

Sun

et al. 2021

Developmental Science

View full text Add to dashboard Cite

show abstract

“…Depending on the subprocesses, language processing can involve a network that include the anterior temporal lobes, dorsomedial PFC, and PCC [ 23 ], while a core LAN network anchored in the anterior insula (AI), superior temporal gyrus (sTG), inferior frontal gyrus (iFG), and middle temporal gyrus (mTG) [ 24 ]. With increasing age, connectivity of the language network would increase during language tasks, but decrease during resting state [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Changes in Default Mode Network Connectivity in Resting-State fMRI in People with Mild Dementia Receiving Cognitive Stimulation Therapy

et al. 2021

View full text Add to dashboard Cite

Group cognitive stimulation therapy (CST) is a 7-week activity-based non-pharmacological intervention for people with mild to moderate dementia. Despite consistent evidence of clinical efficacy, the cognitive and brain mechanisms of CST remain unclear. Theoretically, group CST as a person-centred approach may work through promoting social interaction and personhood, executive function, and language use, especially in people with higher brain/cognitive reserve. To explore these putative mechanisms, structural MRI and resting-state functional MRI data were collected from 16 people with mild dementia before and after receiving CST, and in 13 dementia controls who received treatment as usual (TAU). Voxel-based morphometry (VBM) and resting-state functional connectivity (rs-FC) analyses were performed. Compared with TAU, the CST group maintained the total brain volume/total intracranial volume (TBV/TICV) ratio. Increased rs-FC in the default mode network (DMN) in the posterior cingulate cortex and bilateral parietal cortices nodes was observed in the CST over TAU groups between pre- and post-intervention timepoints. We provided preliminary evidence that CST maintains/enhances brain reserve both structurally and functionally. Considering the role of DMN in episodic memory retrieval and mental self-representation, preservation of personhood may be an important mechanism of CST for further investigation.

show abstract

“…However, some authors have recently argued in favor of state-dependent differences in regional functional connectivity with age (Campbell & Schacter, 2016;Greene, Gao, Scheinost, & Constable, 2018;Samu et al, 2017). In regard to lexical knowledge, recent evidence points toward distinct FC patterns for different tasks (e.g., synonyms, antonyms, picture naming) in older adults (Ferré et al, 2019;Varangis, Razlighi, Habeck, Fisher, & Stern, 2019).…”

Section: Introductionmentioning

confidence: 99%

Task-Induced Functional Connectivity of Picture Naming in Healthy Aging: The Impacts of Age and Task Complexity

Ferré

Jarret

Brambati

et al. 2020

Neurobiology of Language

Self Cite

View full text Add to dashboard Cite

The topological organization of the brain, governed by the capacity of brain regions to synchronize their activity, allows for cost-effective performance during everyday cognitive activity. Functional connectivity is an fMRI method deemed task-specific and demand-dependent. Although the brain undergoes significant changes during healthy aging, conceptual knowledge and word-production accuracy are generally preserved. The exploration of task-induced functional connectivity patterns during active picture naming may thus provide additional information about healthy functional cerebral mechanisms that are specifically adapted to the cognitive activity at hand. The goal of this study is to assess and describe age-related differences in functional connectivity during an overt picture-naming task, as well as to compare age-related differences under complex task demand, defined by lexical frequency. Results suggest both age-specific and task-specific mechanisms. In the context of preserved behavioral performance in a picture-naming task, older adults show a complex array of differences in functional connectivity architecture, including both increases and decreases. In brief, there is increased segregation and specialization of regions that are classically assigned to naming processes. Results also expand on previous word-production studies and suggest that motor regions are particularly subject to age-related differences. This study also provides the first indication that intrinsic task demand, as manipulated by lexical frequency, interacts little with the relationship between age and functional connectivity. Together, these findings confirm the value of task-induced functional connectivity analysis in revealing the brain organization that subserves task performance during healthy aging.

show abstract

Resting-state and vocabulary tasks distinctively inform on age-related differences in the functional brain connectome

Cited by 10 publications

References 159 publications

The development of brain rhythms at rest and its impact on vocabulary acquisition

The development of brain rhythms at rest and its impact on vocabulary acquisition

Changes in Default Mode Network Connectivity in Resting-State fMRI in People with Mild Dementia Receiving Cognitive Stimulation Therapy

Task-Induced Functional Connectivity of Picture Naming in Healthy Aging: The Impacts of Age and Task Complexity

Contact Info

Product

Resources

About