“…Moreover, we hypothesized that (2) specific neurometabolic markers of neurodegeneration (tNAA/tCr) and neuroinflammation (mIns/tCr and tCho/tCr) in the hippocampus would predict worse balance performance of older individuals with MCI more than normative older adults. The latter hypothesis is supported by a number of observations indicating that accelerated neurodegenerative processes in the hippocampus interrupt vestibular functioning, specifically in individuals with MCI ( Jacob et al, 2020 , Micarelli et al, 2017 , Micarelli et al, 2018 , Semenov et al, 2016 , Wang et al, 2022 , Wei et al, 2018 , Wei et al, 2019 ). We further examined the neurometabolic correlates of balance control in relation to measures of tNAA/tCr, tCho/tCr, mIns/tCr, and Glx/tCr in prefrontal, posterior cingulate, and sensorimotor regions due to their expected involvement in attentional control of balance ( Petrigna et al, 2021 , Sugihara et al, 2021 ).…”