Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents

Picchietti, Matthew A.; Picchietti, Daniel L.

doi:10.1016/j.spen.2008.03.005

Cited by 109 publications

(57 citation statements)

References 115 publications

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“…Pediatric studies have demonstrated similar findings with lower than average serum ferratin levels found in around 80% of children with RLS (Picchietti and Stevens 2007;Kotagal and Silber 2004). Furthermore, RLS is more common in females, and it is likely that this is particularly apparent during menstruation and pregnancy (Picchietti and Picchietti 2008). In addition to iron deficiency as a risk factor for RLS, RLS shows particularly high familial vulnerability.…”

Section: Restless Legs Syndrome (Rls): Rls Is Characterised By Unpleamentioning

confidence: 71%

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Barclay¹,

Gregory²

2013

The Neurobiology of Childhood

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Sleep changes throughout the lifespan, with particularly salient alterations occurring during the first few years of life, as well as during the transition from childhood to adolescence. Such changes are partly the result of brain maturation; complex changes in the organisation of the circadian system; as well as changes in daily routine, environmental demands and responsibilities.Despite the automaticity of sleep, given that it is governed by a host of complex mechanisms, there are times when sleep becomes disturbed. Sleep disturbances in childhood are common and may stem from behavioural difficulties or abnormalities in physiological processes and, in some cases manifest into diagnosable sleep disorders. As well as occurring exclusively, childhood sleep disturbances often co--occur with other difficulties. The purpose of this chapter is to outline the neurobiology of typical sleep/wake processes, and describe changes in sleep physiology and architecture from birth to adulthood. Furthermore, common childhood sleep disorders are described as are their associations with other traits, including all of the syndromes presented in this handbook: ASDs, ADHD, schizophrenia, and emotional/ behavioural difficulties. Throughout, we attempt to explain possible mechanisms underlying these disorders and their associations.

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Section: Restless Legs Syndrome (Rls): Rls Is Characterised By Unpleamentioning

confidence: 71%

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Barclay¹,

Gregory²

2013

The Neurobiology of Childhood

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show abstract

“…The presence of cognitive impairment and ADHD has been associated with RLS and PLMs in adults and children. The relationship between RLS and ADHD could occur in several ways: 1) the sleep disorder with poor quality and multiple arousals associated with PLM and RLS could lead to inattention and hyperactivity; 2) RLS and PLM could be co-morbid with ADHD; 3) RLS and PLM, and a subgroup of ADHD could share the same pathophysiological mechanisms of dopaminergic dysfunctioning or changes on iron metabolism; 4) diurnal manifestations of RLS could mimic ADHD symptoms 118,119 .…”

Section: Psychiatric Disordersmentioning

confidence: 99%

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Fröhlich

Éckeli

Bacelar³

et al. 2015

Arq. Neuro-Psiquiatr.

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“…There is evidence of a genetic basis for RLS with PLMS involving chromosome 6p. (Picchietti, 2008) Restless legs syndrome is a diagnosis made based on presenting clinical symptoms such as uncomfortable sensations (e.g,. feeling things crawling or tingling) and the urge to move, both typically involving the lower limbs.…”

Section: Restless Leg Syndrome and Periodic Limb Movement Disordermentioning

confidence: 99%

“…Specific criteria for RLS were published in 2003 by NIH (Allen, 2003). While first observed in adults, RLS has been recognized in children for over fifteen years and is estimated to occur in about 2% of children (Walters, 1994;Picchietti, 1998;Pichietti, 2007;Garcia-Borreguero, 2006;Picchietti, 2008).…”

Section: Restless Leg Syndrome and Periodic Limb Movement Disordermentioning

confidence: 99%

“…The prevalence of PLMD in the general population is not known. However, based on survey information, PLM symptoms are thought to affect about 8-12% of children (Picchietti, 2008). There is evidence that altered dopaminergic central nervous system functioning underlies RLS and PLMD for many individuals.…”

Section: Restless Leg Syndrome and Periodic Limb Movement Disordermentioning

confidence: 99%

See 1 more Smart Citation

ADHD and Sleep Problems in Children

Hastings¹,

Felt²

2012

Current Directions in ADHD and Its Treatment

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Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents

Cited by 109 publications

References 115 publications

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

ADHD and Sleep Problems in Children

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