Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance

Allen, Richard P.; Picchietti, Daniel L.; Garcı́a-Borreguero, Diego; Ondo, William G.; Walters, Arthur S.; Winkelman, John W.; Zucconi, Marco; Ferri, Raffaele; Trenkwalder, Claudia; Lee, Ho-Chang

doi:10.1016/j.sleep.2014.03.025

Cited by 1,263 publications

(991 citation statements)

References 174 publications

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“…However, subjects having chronic pain for any reason, those with impaired cognition, unable to respond to the questionnaire, having psychotic illness, having a previous diagnosis of sleep apnea or parasomnia were excluded from the study. Similarly, patients meeting criteria for RLS were also excluded [15].…”

Section: Methodsologymentioning

confidence: 99%

Prevalence and Predictors of Poor Sleep Quality in Patients on Maintenance Hemodialysis

2017

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Purpose Majority of patients on maintenance hemodialysis complain of poor quality of sleep. Earlier studies show controversial findings with regard to the prevalence and predictors of poor quality of sleep in this group. Hence, the present study was planned. Methods Adult subjects undergoing maintenance hemodialysis were included in this study. Their demographic data, history regarding chronic kidney disease, comorbidities, and details related to hemodialysis were recorded. Sleep quality was assessed using Pittsburg Sleep Quality Index. A total of 201 patients were included in this study. Results Average age of the subjects was 54.7 ± 15.1 years and duration of kidney disease was 37.1 ± 19.8 years. 40.3% subjects were women and 50.7% of sample complained of poor quality sleep. Poor sleepers had less than 3/week dialysis (68.6% among poor sleepers vs. 21.2% among good sleepers; P \ 0.001), nighttime dialysis shift (52.9 vs. 20.2% among good sleepers; P \ 0.001), diabetes mellitus (56.9 vs. 39.4% among good sleepers; P = 0.01), and hypnotic use (P \ 0.001). Similarly, subjects with poor sleep quality were older (57.3 ± 14.3 vs. 52.1 ± 15.4 years among good sleepers; P = 0.01). Binomial logistic regression showed that less than thrice a week dialysis and schedule of maintenance hemodialysis predicted the poor sleep quality. Less than 3/week dialysis increased the odds for poor sleep by 6.6 (P \ 0.001) and afternoon and nighttime maintenance hemodialysis shift by 3.2 (P \ 0.001) and 4.6 (P \ 0.001), respectively. Conclusion Poor sleep is a common complaint in patients on hemodialysis. We found that the evening or night shift of hemodialysis and twice weekly hemodialysis worsened the quality of sleep.

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Section: Methodsologymentioning

confidence: 99%

Prevalence and Predictors of Poor Sleep Quality in Patients on Maintenance Hemodialysis

2017

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“…[6] Subjects who fulfilled all five criteria were diagnosed as RLS. Updated integrated RLS diagnostic criteria were listed in Table 1.…”

Section: Assessment Parametersmentioning

confidence: 99%

“…[6,7] Diagnosis is based on clinical features and the diagnostic criteria suggested by International RLS Study group (IRLSSG). [6] However, RLS still remains underdiagnosed probably due to lack of accurate information about the disease. [8] The etiology of pediatric RLS is poorly understood.…”

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confidence: 99%

Restless legs syndrome in children with allergic rhinitis: A comparative study on frequency, severity and sleep quality

Filiz¹

2018

Turk J Phys Med Rehab

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Objectives: This study aims to investigate the frequency and severity of restless legs syndrome (RLS) and its relationship with sleep quality in children with allergic rhinitis (AR) with the hypothesis that comorbid RLS may be an additional causative factor of sleep disturbances in pediatric AR. Patients and methods:A total of 143 children with AR (aged 8-18 years) and 144 healthy control subjects (aged 8-18 years) were included. The diagnosis of AR was established on history, clinical examination and skin prick test according to the Allergic Rhinitis and its Impact on Asthma guidelines. Presence of RLS was determined using the International RLS study group (IRLSSG) criteria. The severity of RLS was assessed using the IRLSSG rating scale. Sleep quality was evaluated by Pittsburgh Sleep Quality Index (PSQI).Results: Thirteen patients (9.1%) in AR group, and six children (4.2%) in control group had RLS (p=0.159). The frequency of RLS in AR group was higher than two folds when compared to the control group; however, the difference was not statistically significant. Restless legs syndrome severity score was significantly higher in AR group than control group (15.00 [11][12][13][14][15][16][17][18][19][20] and 11.00 [10][11][12][13][14][15][16] respectively, p=0.046). Total PSQI scores were similar between groups. Also, no significant differences were observed in total PSQI scores of AR patients with or without RLS. Conclusion:Restless legs syndrome was not more common but was more severe in children with AR. There was no evidence that RLS has an obvious effect on sleep quality in children with AR.

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“…Because other medical or behavioral conditions can mimic symptoms of RLS and in order to improve specificity in the diagnosis of RLS, it has been recommended by the International Restless Legs Syndrome Study Group that certain conditions be considered in the differential diagnosis. 20 As a result, an additional nine participants who indicated that they had arthritis, anxiety, or peripheral neuropathy on a health history questionnaire were excluded from this analysis. Three of the nine participants who met the other criteria for RLS were eliminated, one who reported arthritis and two who reported anxiety.…”

Section: Participantsmentioning

confidence: 99%

Symptoms of Restless Legs Syndrome in Biological Caregivers of Children with Autism Spectrum Disorders

Russell

Baldwin

McClain

et al. 2017

Journal of Clinical Sleep Medicine

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Study Objectives: In this study, we investigated the prevalence of symptoms of restless legs syndrome (RLS) in biological caregivers of children with a diagnosis of autism spectrum disorder (ASD).The relationship of RLS symptoms to caregiver health-related quality of life (HRQoL) was also examined. Finally, we compared the sleep quality and daytime behaviors of children with ASD in caregivers with and without symptoms of RLS. Methods: Biological caregivers (n = 50) of children ages 6 to 11 y with a diagnosis of ASD completed a Sleep Habits Questionnaire (SHQ) that included RLS as determined by four questions. HRQoL was assessed using the Medical Outcomes Survey (MOS) 12-Item Short Form (SF-12). Caregivers also completed the Children's Sleep Habits Questionnaire (CSHQ) and Child Behavior Checklist (CBCL6/18). Results: Eleven caregivers (22%) fit the criteria for RLS symptomatology and caregivers with RLS reported poorer mental health. Caregivers with RLS described more night waking and greater internalized behavior problems in their children with ASD than the caregivers without RLS. Conclusions: Biological caregivers of children with ASD demonstrated a high prevalence of RLS symptoms and poorer mental health. RLS is known as a sleep disorder that has strong heritability, and it is possible that many of the children with ASD also have symptoms of RLS. RLS as a possible disruptor of sleep should be considered in caregivers and in their children with ASD. Keywords: autism spectrum disorder, caregivers, health-related quality of life, restless legs syndrome Citation: Russell M, Baldwin C, McClain D, Matthews N, Smith C, Quan SF. Symptoms of restless legs syndrome in biological caregivers of children with autism spectrum disorders.

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Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance

Cited by 1,263 publications

References 174 publications

Prevalence and Predictors of Poor Sleep Quality in Patients on Maintenance Hemodialysis

Prevalence and Predictors of Poor Sleep Quality in Patients on Maintenance Hemodialysis

Restless legs syndrome in children with allergic rhinitis: A comparative study on frequency, severity and sleep quality

Symptoms of Restless Legs Syndrome in Biological Caregivers of Children with Autism Spectrum Disorders

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