Restrictive Left Ventricular Filling Pattern with Preserved Systolic Function Assessed by Doppler Echocardiography: Clinical, Echocardiographic and Prognostic Implications

Boccalandro, Fernando; Loghin, Catalin; Darwood, Susan; Seung-Ho, Kang; Barasch, Eddy

doi:10.1159/000066318

Cited by 4 publications

(1 citation statement)

References 28 publications

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“…A restrictive pattern of left ventricular filling (RPLVF) and its prognostic implications have been extensively studied in patients with impaired [1, 2, 3]and preserved left ventricular systolic function [4, 5]. The presence of RPLVF is associated with elevated left ventricular filling pressure in patients with impaired systolic function [6], identifying a group of patients with worse symptoms and poor prognosis [7, 8].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Cardiovascular Death in Patients with a Left Ventricular Restrictive Filling Pattern of the Mitral Inflow

Boccalandro¹,

Loghin²,

Seung-Ho³

et al. 2004

Cardiology

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The survival, clinical and echocardiographic variables and the predictors of cardiovascular death were determined for a group of 168 patients (mean age 63 ± 13 years; 65 females; mean left ventricular ejection fraction 32 ± 10%) with restrictive filling of the left ventricle and depressed systolic function after a mean follow-up period of 2.7 ± 1 years. Shorter deceleration time (DT) of the mitral inflow was the only variable significantly different between survivors and nonsurvivors (p < 0.05) and the only predictor of death found by multivariate logistic regression analysis (odds ratio 2.2, 95% confidence interval 1.7–3.6). In this patient population, a DT of the early wave of the mitral inflow <140 ms identified the patients with the highest risk of cardiac death. DT is a practical echocardiographic parameter for risk stratification of patients with significant left ventricular systolic dysfunction and restrictive filling of the left ventricle.

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