Result of therapy for Hodgkin Lymphoma (HL): a report from the Chilean pediatric National Cancer Program (PINDA)

V, Emma Concha; Cordova, M; Becker, A; Rizzardini, Carlos; Salgado, Carlos I. Valencia; Perez, Victoria; Fernández, Emilio; Espinoza, Felipe; Martínez, P.; Valero, Miguel; Neira, L; Arriagada, M

doi:10.1055/s-0040-1701857

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“…49,50 Chile also has a long history of executing collaborative clinical trials through the Programa Infantil de Drogas Antineopl ásicas de Chile (PINDA), founded in 1988. 51 PINDA has developed numerous protocols for multiple tumor types [52][53][54][55] with extensive international collaboration, including with I-BFM 56 and St Jude Children's Research Hospital (SJCRH). 57 GALOP was founded in 2008 in Uruguay with the support of COG to execute pediatric cancer clinical trials in Brazil, Argentina, Uruguay, and Chile.…”

Section: Pediatric Oncology Clinical Trial Collaborative Groups By Re...mentioning

confidence: 99%

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Major

Palese

Ermis

et al. 2022

JCO Global Oncology

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PURPOSE The global pediatric oncology clinical research landscape, particularly in Central and South America, Africa, and Asia, which bear the highest burden of global childhood cancer cases, is less characterized in the literature. Review of how existing pediatric cancer clinical trial groups internationally have been formed and how their research goals have been pursued is critical for building global collaborative research and data-sharing efforts, in line with the WHO Global Initiative for Childhood Cancer. METHODS A narrative literature review of collaborative groups performing pediatric cancer clinical research in each continent was conducted. An inventory of research groups was assembled and reviewed by current pediatric cancer regional and continental leaders. Each group was narratively described with identification of common structural and research themes among consortia. RESULTS There is wide variability in the structure, history, and goals of pediatric cancer clinical trial collaborative groups internationally. Several continental regions have longstanding endogenously-formed clinical trial groups that have developed and published numerous adapted treatment regimens to improve outcomes, whereas other regions have consortia focused on developing foundational database registry infrastructure supported by large multinational organizations or twinning relationships. CONCLUSION There cannot be a one-size-fits-all approach to increasing collaboration between international pediatric cancer clinical trial groups, as this requires a nuanced understanding of local stakeholders and resources necessary to form partnerships. Needs assessments, performed either by local consortia or in conjunction with international partners, have generated productive clinical trial infrastructure. To achieve the goals of the Global Initiative for Childhood Cancer, global partnerships must be sufficiently granular to account for the distinct needs of each collaborating group and should incorporate grassroots approaches, robust twinning relationships, and implementation science.

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Section: Pediatric Oncology Clinical Trial Collaborative Groups By Re...mentioning

confidence: 99%

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Major

Palese

Ermis

et al. 2022

JCO Global Oncology

View full text Add to dashboard Cite

show abstract

Result of therapy for Hodgkin Lymphoma (HL): a report from the Chilean pediatric National Cancer Program (PINDA)

Cited by 1 publication

References 0 publications

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

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