Resultados de la aplicación de radiocirugía con acelerador lineal en pacientes con neuralgia del trigémino

BACKGROUND: Patients with trigeminal neuralgia (TN) secondary to mass lesions are typically treated by directly addressing the underlying pathology. In cases of TN not alleviated by treatment of the pathology, percutaneous balloon compression (PBC) and glycerol rhizotomy (Gly) are simple and effective ways to alleviate pain. However, there is limited literature on the use of these techniques for patients with TN caused by mass lesions. OBJECTIVE: To describe the use of PBC/Gly to treat mass lesion–related TN. METHODS: We report a retrospective, single-institution, descriptive case series of patients who presented with TN secondary to tumor or mass-like inflammatory lesion from 1999 to 2021. Patients with primary, idiopathic, or multiple sclerosis–related TN were excluded. Outcomes included Barrow Neurological Institute (BNI) pain intensity and hypesthesia scores, pain persistence, and postoperative complications. RESULTS: A total of 459 procedures were identified, of which 16 patients met the inclusion criterion (14 PBC and 2 Gly). Of the 15 patients with tumors, 12 had TN pain despite prior tumor-targeted radiation. Short-term (<3 months) BNI pain intensity improvement occurred in 15 (93.8%) patients. The mean follow-up was 54.4 months. Thirteen (81.3%) patients were pain-free (Barrow Neurological Institute pain intensity scale: IIIa–50%; I–25.0%; II–6.3%) for a mean of 23.8 (range 1-137) months. Ten patients (62.5%) had pain relief for ≥6 months from first procedure. New facial numbness developed immediately postprocedure in 8 (50%) patients. Transient, partial abducens nerve palsy occurred in 1 patient. CONCLUSION: PBC/Gly is an effective option for medically refractory TN in patients with mass-associated TN and is a viable option for repeat treatment.

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Percutaneous Rhizotomy of the Gasserian Ganglion in Patients With Mass Lesion–Associated Trigeminal Neuralgia: A Case Series

Petitt

Murayi

Potter

et al. 2023

Operative Neurosurgery

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Resultados de la aplicación de radiocirugía con acelerador lineal en pacientes con neuralgia del trigémino

Abstract: According to our results, radiosurgery is an effective treatment for trigeminal neuralgia, with few side effects. Typical pain seems to be a good predictor of pain relief.

Cited by 1 publication

References 32 publications

Percutaneous Rhizotomy of the Gasserian Ganglion in Patients With Mass Lesion–Associated Trigeminal Neuralgia: A Case Series

Percutaneous Rhizotomy of the Gasserian Ganglion in Patients With Mass Lesion–Associated Trigeminal Neuralgia: A Case Series

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