Results after change of treatment policy for rectal cancer – report from a single hospital in China

Wu, Aiwen; Gu, Jin; Wang, J.; Ye, S.W.; An, Q.; Yao, Yunfeng; Zhan, Tiancheng

doi:10.1016/j.ejso.2006.12.011

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Cited by 7 publications

(5 citation statements)

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“…The local recurrence rate was 6.7% and long‐term overall survival rate was 92.6% . In another report the local recurrence rate after TME was around 6%, consistent with results from Europe, but long‐term survival was not improved .…”

Section: Advanced Rectal Cancersupporting

confidence: 67%

Current status of rectal cancer treatment in China

Chen

2013

Colorectal Disease

Self Cite

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Section: Advanced Rectal Cancersupporting

confidence: 67%

Current status of rectal cancer treatment in China

Chen

2013

Colorectal Disease

Self Cite

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“…Compared with Western countries, 70% of CRC arises in the rectum, whereas 30% occurs in the colon 1 2. Surgery is the mainstay of comprehensive therapy for rectal cancer 3. However, local recurrence and distant metastases remain two critical factors that affect the long-term survival and quality of life.…”

Section: Introductionmentioning

confidence: 99%

Lymph node distribution and pattern of metastases in the mesorectum following total mesorectal excision using the modified fat clearing technique

et al. 2011

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Small LN detection increased the accuracy of N staging by 20% in this study. The incidence of metastasis was the same among the anterior, bilateral and posterior areas of the mesorectum. An increased incidence of mLN metastasis in small LNs was associated with more advanced T staging. mLN metastasis rates in both middle and low rectal cancer were higher in the distal mesorectum than that in the proximal mesorectum. LN number and density were not consistent with spread of the primary tumour. Distal mLNs were found in 35% of cases of both middle and distal rectal cancer, implying a need for TME in both.

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“…Most of the TME studies report a median follow-up of 5 years or less. 7,[11][12][13][14][15] However, an analysis of 169,658 French patients with colorectal cancer who were initially treated with curative intent estimated that the time to cure is 9.3 years. 16 Similarly, a Japanese group found cumulative recurrence rates in rectal cancer of 89% at 5 years, 98% at 7 years, and 100% at 10 years.…”

mentioning

confidence: 99%