Results following resection for stage IV gastric cancer: Are better outcomes observed in selected patient subgroups?

Lim, S. H.; Muhs, Bart E.; Marcus, Stuart G.; Newman, Elliot; Berman, Russell S.; Hiotis, Spiros P.

doi:10.1200/jco.2004.22.14_suppl.4207

Cited by 5 publications

(8 citation statements)

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“…Heterogeneous studies indicate a potential role of surgery in patients with metastatic gastric cancer (7,(12)(13)(14)(15)(16)(17)(18)(22)(23)(24)(25)(26)(27)(28). Similar as other aggressive treatment strategies, i.e.…”

Section: Discussionmentioning

confidence: 99%

“…In the literature heterogeneous results exist concerning this issue. Whereas some studies report a survival benefit for particular sites (7,23), some do not (15,18). Single metastases (12,33) or a limited number of metastases (8,34) have been reported to be prognostic advantageous compared to multiple or extended metastatic spread.…”

Section: Discussionmentioning

confidence: 99%

“…During the last decade the value of surgery in esophago-gastric adenocarcinoma with limited metastatatic disease has increased steadily and survival data justifies this approach (7,8,11,12,15,16,18,24,27). To define reasonable inclusion criteria and to improve comparability of studies interdisciplinary concepts including realistic surgical recommendations for complete resections are warranted.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

“…Several factors have been suggested as indicators for potential benefits from resection, i.e. response to induction therapy (12,13), number and pattern of metastasis (12)(13)(14)(15)(16)(17), performance status (14,15), and extent of the primary tumour (16,18). Previously published prognostic factors include the delivery of chemotherapy, resection, length of the primary tumour, number of metastatic sites and histopathological response (1,2,7).…”

Section: Introductionmentioning

confidence: 99%

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Surgery in oesophago-gastric cancer with metastatic disease: Treatment, prognosis and preoperative patient selection

Schmidt

Alldinger

Blank

et al. 2015

European Journal of Surgical Oncology (EJSO)

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Surgery in oesophago-gastric cancer with metastatic disease: Treatment, prognosis and preoperative patient selection

Schmidt

Alldinger

Blank

et al. 2015

European Journal of Surgical Oncology (EJSO)

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“…3 9 Intraoperativer Situs nach systematischer D2-Lymphadenektomie tion weist die palliative Resektion in der Regel eine niedrige Letalität auf. Das Gesamtüberleben könnte bei palliativen Resektionen verlängert sein, allerdings wird in den vorliegenden Studien die Lebensqualität nicht entsprechend berücksich-tigt [18].…”

Section: Introductionunclassified

Aktuelle S3-Leitlinie zur Chirurgie des Magenkarzinoms

Meyer

Hölscher

Lordick

et al. 2011

Chirurg

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The current S3 guidelines on the diagnosis and treatment of gastric carcinoma including those of the esophagogastric junction describe optimal clinical practice based on a high level of evidence and expert consensus from different medical disciplines. Endoscopy and performance of multiple biopsies is the standard approach to detect malignant tumors in the upper gastrointestinal tract. Further diagnostic procedures are necessary to evaluate the tumor stage. With the exception of mucosal carcinomas, surgical therapy is the cornerstone of curative treatment in all potentially resectable stages. In locally advanced carcinomas perioperative chemotherapy should be carried out and in high-seated tumors preoperative radiochemotherapy might be an alternative option. Palliative surgical resection should be avoided in disseminated asymptomatic stages. In a palliative situation complications of the tumor should primarily be treated by interventional or conservative procedures.

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