Results for a Series of 697 Arteriovenous Malformations Treated by Gamma Knife

Abstract

GKRS yielded a good long-term clinical outcome in most patients. Certain angiographic features of brain AVMs such as a well-defined nidus and undilated feeder arteries contribute to AVM occlusion by RS. GKRS can be regarded as the treatment of choice for AVMs <6 cm(3), even after bleeding.

WITHDRAWN: Predictors for complete obliteration of arteriovenous malformations following stereotactic radiosurgery

“…Although two studies [11,19] showed that there was no association between the SM grade and obliteration rate, we found that AVM with lower SM grade had a higher obliteration rate. This may be related a smaller AVM volume observed in lower SM grade [21]. Although the SM grade could be an independent predictor for obliteration, RBAS had a stronger predictive ability than SM grade, with OR of 2.08 and 1.66 respectively.…”

“…Three articles [10,11,14] demonstrated a trend towards lower obliteration rates in previously embolized AVM, however, there results didn't reach statistical significance. Embolization could result in making the nidus more diffuse, making targeting the nidus at the time of radiosurgery more difficult [21]. However, Zabel-du et al [33] suggested that the AVM of ≥ 3 cm in diameter had lower obliteration rates than AVM with a smaller diameter < 3 cm (92% VS 60%).…”

“…Six-hundred and seventy (670) unrelated articles were excluded. After reviewing the full texts of the 31 selected articles, 10 articles [10][11][12][13][14][15][16][19][20][21] met the inclusion criteria and where selected for the analysis. From the selected articles, 10 predictive factors were identified and subsequently analyzed, including rupture of AVM, deep location, noneloquence, craniotomy surgery, prior embolization, volume of AVM, max diameter, gender, age, and high margin dose.…”

Radiosurgery for Cerebral Arteriovenous Malformations in Elderly Patients: Effect of Advanced Age on Outcomes After Intervention

“…The correlation of RBAS with post-treatment outcomes has not been consistently observed in large AVM radiosurgery series (15,17,19,27,37,43,48). The VRAS, which was developed at our institution to predict favorable outcome (AVM obliteration, no latency period hemorrhage, no permanent RIC) after AVM radiosurgery, did not include patient age, but rather AVM volume, history of hemorrhage, and eloquent nidus location (49).…”

Cerebral Arteriovenous Malformations and Epilepsy, Part 2: Predictors of Seizure Outcomes Following Radiosurgery

“…Seizures are the second most common clinical manifestation of cerebral arteriovenous malformations (AVM) following hemorrhage and are the most common presentation of patients with unruptured AVMs (18,42,45,57,59).…”