Results in Laparoscopic Living Donor Nephrectomy: A Multicentric Experience

Effects of nephrectomy on respiratory function and quality of life of living donors: a longitudinal study

“…In the present study, less respiratory function impairment in healthy donors who underwent nephrectomy was observed compared with other open upper abdominal surgeries 5 , 7 , 14 , 23 . The present findings demonstrate that FVC and FEV 1 decreased by approximately 30% on the 1 st PO day; these data differ from those found in other upper abdominal surgeries in which the variables were typically reduced by approximately 50% 24 - 26 . In addition, FVC returned to preoperative values on the 5 th PO day, which normally occurs seven or more days after surgery 7 , 27 .…”

“…With respect to respiratory muscle strength, a 40% decrease in MIP and a 47% decrease in MEP was observed on the 1 st PO day, with a tendency to return to baseline values on the subsequent postoperative days; these data are similar to those previously described in the literature 12 , 26 , 28 . Several possibilities have been suggested in the literature to justify the change in respiratory function and muscle strength during the postoperative period, such as decreasing pain, choice of surgical incision site, duration of anesthesia and surgery, but the primary cause is reported to be diaphragmatic mobility dysfunction due to the reflex inhibition of the phrenic nerve 6 , 7 , 9 .…”

“…Although nephrectomy was performed by conventional open surgery, our results are similar to those found in patients undergoing laparoscopic nephrectomy 25 , 26 . Studies have suggested that laparoscopic surgery is associated with decreased analgesia, reduced hospital stay, and early return to preoperative conditions 25 , 26 .…”

“…Although nephrectomy was performed by conventional open surgery, our results are similar to those found in patients undergoing laparoscopic nephrectomy 25 , 26 . Studies have suggested that laparoscopic surgery is associated with decreased analgesia, reduced hospital stay, and early return to preoperative conditions 25 , 26 . A recent systematic review 25 , however, demonstrated that when comparing laparoscopic and open surgeries, the incidence of general complications such as reoperation, early graft loss and delayed graft function are similar in both procedures.…”

“…A recent systematic review 25 , however, demonstrated that when comparing laparoscopic and open surgeries, the incidence of general complications such as reoperation, early graft loss and delayed graft function are similar in both procedures. Ferrario et al 26 assessed 46 donors undergoing laparoscopic nephrectomy and, as in the present study, found no postoperative complications during the hospital stay; however, although our sample underwent open nephrectomy, shorter durations of surgery (105.04±21 vs. 170±45 minutes) and of hospital stay (3 vs. 5±1 days) were observed.…”