1996
DOI: 10.1001/archsurg.1996.01430130073014
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Results of 280 Liver Resections for Hepatocellular Carcinoma

Abstract: The recent results of liver resection for hepatocellular carcinoma are generally satisfactory; however, the recurrence rate is still high.

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Cited by 207 publications
(133 citation statements)
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References 26 publications
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“…the cumulative probability of avoiding both death and disease recurrence) predominantly fall within the following ranges: 50-80% at 1 year, 30-50% at 3 years, 15-40% at 5 years and 8-20% at 10 years. 158,166,173,174,[176][177][178][179][180][181][182][183][184][185][186][187][188][189][190][191][192][193] …”
Section: Disease Recurrencementioning
confidence: 99%
“…the cumulative probability of avoiding both death and disease recurrence) predominantly fall within the following ranges: 50-80% at 1 year, 30-50% at 3 years, 15-40% at 5 years and 8-20% at 10 years. 158,166,173,174,[176][177][178][179][180][181][182][183][184][185][186][187][188][189][190][191][192][193] …”
Section: Disease Recurrencementioning
confidence: 99%
“…Hepatocellular carcinoma (HCC) accounts for more than 90% of all primary liver cancers and represents approximately 40% of all cancers in South-East Asia, Japan and Africa (Akriviadis et al, 1998). The majority of these HCC cases is often inoperable (Okuda et al, 1985) and the 5-year survival rate is limited to 25-50% after surgery (Colombo, 1992;Lai et al, 1995;Takenaka et al, 1996). Long-term survival is uncommon owing to frequent recurrence, metastasis or the development of new primaries (Lai, 1994;Huguet, 2000) and the current adjuvant or palliative treatment modalities are not able to conclusively prolong survival of patients with HCC (Chan et al, 2000).…”
Section: Introductionmentioning
confidence: 99%
“…The recurrent peak is found at six months or 1 year after operation and most of the early postoperative recurrence is intrahepatic metastasis [18] , which is attributed to the characteristics of vascular invasion propensity of HCCs. The appearance of tiny tumors through venous invasion in the liver is the main sign for potential HCC recurrence after surgery [19][20][21][22][23][24][25][26][27][28][29] . The intrahepatic metastasis of the tumor cells through the portal venous system is believed to be an important mechanism for HCC recurrence [24,30,31] .…”
Section: Discussionmentioning
confidence: 99%