Results of a 13 week safety assurance study with rats fed grain from glyphosate tolerant corn

Hammond, Bruce G.; Dudek, R.; Lemen, Joan K.; Nemeth, Margaret A.

doi:10.1016/j.fct.2004.02.013

Cited by 109 publications

(123 citation statements)

References 16 publications

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“…Study Objectives Séralini et al (2012b) state that they replicated and improved the study by Hammond et al (2004) and "in order to know if the statistical findings (in 90 days) were biologically relevant or not on the long term". This is not reflected in the analysis and reporting in Séralini et al (2012a).…”

Section: 1mentioning

confidence: 99%

Final review of the Séraliniet al. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology

Authority¹

2012

EFSA Journal

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On 19 September 2012, Séralini et al. published online in the scientific journal Food and Chemical Toxicology a publication describing a 2‐year feeding study in rats investigating the health effects of genetically modified maize NK603 with and without Roundup WeatherMAX® and Roundup® GT Plus alone (both are glyphosate‐containing plant protection products). As requested by the European Commission, EFSA reviewed this publication taking into consideration assessments conducted by Member States and any clarification given by the authors. The assessments of Member States and EFSA revealed an overall agreement. The study as reported by Séralini et al. was found to be inadequately designed, analysed and reported. The authors of Séralini et al. provided a limited amount of relevant additional information in their answer to critics published in the journal Food and Chemical Toxicology. Taking into consideration Member States’ assessments and the authors’ answer to critics, EFSA reaches similar conclusions as in its first Statement (EFSA 2012). The study as described by Séralini et al. does not allow giving weight to their results and conclusions as published. Conclusions cannot be drawn on the difference in tumour incidence between treatment groups on the basis of the design, the analysis and the results as reported. Taking into consideration Member States’ assessments and the authors’ answer to critics, EFSA finds that the study as reported by Séralini et al. is of insufficient scientific quality for safety assessments. EFSA concludes that the currently available evidence does not impact on the ongoing re‐evaluation of glyphosate and does not call for the reopening of the safety evaluations of maize NK603 and its related stacks. EFSA's evaluation of the Séralini et al. article is in keeping with its role to review relevant scientific literature for risk assessment on an ongoing basis to ensure that the advice it provides is up‐to‐date.

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Section: 1mentioning

confidence: 99%

Final review of the Séraliniet al. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology

Authority¹

2012

EFSA Journal

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“…PAT is specific and does not possess food toxins or allergens in human food and animal feed (Hérouet et al, 2005). The lack of toxicity or allergenicity of EPSPS has also been proved (Hammond et al, 2004). However, some consumers are opposed to the use of these selectable markers because they are derived from bacterial or fungal DNA.…”

Section: The Use Of Mutated Als Genes As Selective Markersmentioning

confidence: 99%

Transgenic Tall Fescue and Maize with Resistance to ALS-Inhibiting Herbicides

Sato¹,

Takamizo²,

Horita³

et al. 2011

Herbicides, Theory and Applications

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“…Some studies assessed the safety of GM plants and report some changes in serum chemistry due to GM foods utilization (Hammond et al 2004(Hammond et al , 2006Elsanhoty et al 2004Elsanhoty et al , 2006. It was observed a few statistically significant differences between rats fed on GM corn (MON 810) and its control as well as GM potato Spunta and its control (Elsanhoty et al 2004(Elsanhoty et al , 2006.…”

Section: Introductionmentioning

confidence: 99%

Composition and rheological properties of flour and dough from genetically modified wheat (Triticum aestivum L.) Hi-Line 111

Elfattah

Elsanhoty

Ramadan

et al. 2016

Cereal Research Communications

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The main objective of this work was to evaluate the composition, nutritional, physical and rheological properties of wheat flour and dough from genetically modified wheat (Triticum aestivum L.) Hi-Line 111 (GMW) compared to conventional wheat (non-GMW). Analyses were conducted to measure the proximate chemical composition with references to 18 components including total solid, protein, lipids, crude fiber, ash, carbohydrate, minerals, amino acids, and fatty acids. In addition, physical and rheological properties such as water absorption, arrival time, dough development time, stability value, dough weakening value, extensibility of dough, resistance to extension, and ratio of resistance/extensibility were evaluated. The results showed that there were no significant differences between GMW and non-GMW in terms of chemical composition. Results revealed the presence of saturated and unsaturated fatty acids wherein there were no significant differences between GMW and its counterpart in the levels of fatty acids. In addition, there were no significant differences on the levels of amino acids. In addition, there were no significant differences between the GMW and non-GMW in the physical and rheological properties. From these results, it can be concluded that GMW Hi-Line 111 is confirmed to have nearly the composition and rheological properties as non-GMW.

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Results of a 13 week safety assurance study with rats fed grain from glyphosate tolerant corn

Cited by 109 publications

References 16 publications

Final review of the Séraliniet al. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology

Final review of the Séraliniet al. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology

Transgenic Tall Fescue and Maize with Resistance to ALS-Inhibiting Herbicides

Composition and rheological properties of flour and dough from genetically modified wheat (Triticum aestivum L.) Hi-Line 111

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