Objective: on the basis of a literature review, to select the most convenient method of a diagnostic block of the superior and middle cluneal nerves that can be used in wide clinical practice.Material. Publications that are deposited in PubMed resources and information portal eLIBRARY.RU and contain information on the application of diagnostic blocks of the superior and middle cluneal nerves were studied and analyzed.Results. The most important aspects dealing with the prospects of the application of diagnostic blocks in neuropathy of the superior and middle cluneal nerves have been selected.Conclusion. There is a variety of approaches to nerve block techniques and assessment of its results. Therefore, it is necessary to develop a step-by-step method for conducting diagnostic and therapeutic blocks in neuropathy of the superior and middle cluneal nerves that is convenient for use in wide clinical practice.