Results of direct percutaneous transluminal coronary angioplasty in octogenarians

Laster, Steven B.; Rutherford, Barry D.; Giorgi, Lee V.; Shimshak, Thomas M.; McConahay, David R.; Johnson, Warren L.; Huber, Kenneth C.; Ligon, Robert W.; Hartzler, Geoffrey O.

doi:10.1016/s0002-9149(97)89126-6

Cited by 50 publications

(38 citation statements)

References 13 publications

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“…In our investigation, in agreement with previous data in octogenarians, 5,6 primary PCI performed in STEMI patients aged ≥85 years achieves a successful angiographic result in most cases and is associated with a low rate of re-infarction and CVA during hospitalization. The incidence of bleeding complications was higher than that reported in other series, 6 and was mainly related to access-site complications.…”

Section: Discussionsupporting

confidence: 92%

“…Recently, Hassani et al reported an in-hospital mortality rate of 15% in octogenarians with acute coronary syndrome undergoing PCI and drug-eluting stent implantation. 1 In our investigation, the mortality rate of STEMI patients ≥85 years without cardiogenic shock was comparable (7.7%) with those previously described, 1,5,6 whereas our patients with cardiogenic shock had a mortality rate of 90%, which is higher than previously reported. 1,5,6 In our series, long-term survival of patients aged ≥85 years with STEMI treated with primary PCI was good, being that the post discharge survival was not different from that expected in a population of the same age.…”

Section: Discussionsupporting

confidence: 85%

“…Laster et al reviewed the cumulative experience of primary PCI in 55 octogenarians over a period of 13 years and reported an overall 30-day mortality rate of 16%; in particular, a mortality rate of 67% for patients with cardiogenic shock on presentation and of 10% for patients without cardiogenic shock. 6 Similar data were reported by Antoniucci et al, 5 who evaluated 55 octogenarian STEMI patients undergoing primary PCI. Recently, Hassani et al reported an in-hospital mortality rate of 15% in octogenarians with acute coronary syndrome undergoing PCI and drug-eluting stent implantation.…”

Section: Discussionsupporting

confidence: 74%

“…The incidence of bleeding complications was higher than that reported in other series, 6 and was mainly related to access-site complications. It is interesting to note that the incidence of acute renal failure in STEMI patients aged ≥85 years is comparable with that previously reported in unselected patients undergoing urgent coronary angiography.…”

Section: Discussioncontrasting

confidence: 68%

“…[5][6][7] In the present investigation we aimed to evaluate the short-and long-term outcomes of 88 consecutive very old (age ≥85 years) patients with STEMI undergoing primary angioplasty.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Effectiveness and Safety of Routine Primary Angioplasty in Patients Aged .GEQ.85 Years With Acute Myocardial Infarction

Valente

Lazzeri

Salvadori

et al. 2008

Circ J

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show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 85%

Section: Discussionsupporting

confidence: 74%

Section: Discussioncontrasting

confidence: 68%

mentioning

confidence: 99%

See 3 more Smart Citations

Effectiveness and Safety of Routine Primary Angioplasty in Patients Aged .GEQ.85 Years With Acute Myocardial Infarction

Valente

Lazzeri

Salvadori

et al. 2008

Circ J

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show abstract

Feature topic: Clinical use of abciximab: Coronary artery stenting for suboptimal PTCA results in acute myocardial infarction in patients treated with abciximab: Early and six-month outcome

Murdock¹,

Logemann²,

Hoffmann³

et al. 1997

Cathet. Cardiovasc. Diagn.

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The dilemma of success: Percutaneous coronary interventions in patients ≥ 75 years of age—successful but associated with higher vascular complications and cardiac mortality

Assali

Moustapha

Sdringola

et al. 2003

Cathet Cardio Intervent

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Elderly patients are increasingly referred to percutaneous coronary interventions (PCIs). Recent reports suggest complications rates are declining in the elderly. We sought to determine whether procedural and in-hospital outcomes are different in patients aged > or = 75 years undergoing nonemergent PCI as compared to patients age < 75 years. The outcome of 266 consecutive patients age > or = 75 years undergoing nonemergent PCI was compared to that of 1,681 consecutive patients age < 75 years. Compared with younger patients, greater proportions of elderly patients were women and had a history of hypertension, peripheral vascular disease, and cerebral vascular events. Elderly patients had more extensive coronary involvement. Procedural success was similar in both groups (94%). The in-hospital cardiac death rate was significantly higher in the elderly patients (2.3% vs. 0.7%; P = 0.03). Aged patients also had a significantly higher incidence of vascular and bleeding complications. Blood transfusion was required more often in the elderly group (4.5% vs. 2.6%; P = 0.07). The hospitalization length was significantly higher in the elderly group (4.1 +/- 6.0 vs. 2.5 +/- 4.3 day; P = 0.0004). By multivariate logistic regression (adjusted for baseline clinical and angiographic variables), age > or = 75 years was found to be an independent predictor of in-hospital cardiac death (odds ratio = 3.9; 95% CI = 1.3-11.5; P = 0.015). Although PCI is technically successful in patients aged > or = 75 years; it is associated with more acute cardiac and vascular complications and higher in-hospital cardiac mortality.

show abstract

Results of direct percutaneous transluminal coronary angioplasty in octogenarians

Cited by 50 publications

References 13 publications

Effectiveness and Safety of Routine Primary Angioplasty in Patients Aged .GEQ.85 Years With Acute Myocardial Infarction

Effectiveness and Safety of Routine Primary Angioplasty in Patients Aged .GEQ.85 Years With Acute Myocardial Infarction

Feature topic: Clinical use of abciximab: Coronary artery stenting for suboptimal PTCA results in acute myocardial infarction in patients treated with abciximab: Early and six-month outcome

The dilemma of success: Percutaneous coronary interventions in patients ≥ 75 years of age—successful but associated with higher vascular complications and cardiac mortality

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