Results of Patch-Tests from Santa Casa de Belo Horizonte Dermatology Clinic, Belo Horizonte, Brazil, from 2003 to 2010

Rodrigues, Dulcilea Ferraz; Neves, Daniela Rezende; Pinto, Jackson Machado; Alves, Marcos Felipe Fonseca; Fulgêncio, Ana Cristina Franco

doi:10.1590/s0365-05962012000500028

Cited by 14 publications

(17 citation statements)

References 4 publications

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“…2-6 This is due to its presence in preparations like vaccines, contact lenses solutions and tattoo ink, which favors the contact of the population with this substance.…”

mentioning

confidence: 99%

Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period

Duarte¹,

Tanaka²,

Suzuki³

et al. 2013

An. Bras. Dermatol.

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A retrospective study was carried out between 2006-2011. Six hundred and eighteen patients with suspected allergic contact dermatitis underwent the standard patch test series recommended by the Brazilian Contact Dermatitis Research Group. The aim of our study was to evaluate the variation of positive patch-test results from standard series year by year. The most frequently positive allergens were: nickel sulfate, thimerosal and potassium bichromate. Decrease of positive patch-test results over the years was statistically significant for: lanolin (p=0.01), neomycin (p=0.01) and anthraquinone (p=0.04). A follow-up study should be useful in determining which allergens could be excluded from standard series, as they may represent low sensitization risk.

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“…2-6 This is due to its presence in preparations like vaccines, contact lenses solutions and tattoo ink, which favors the contact of the population with this substance.…”

mentioning

confidence: 99%

Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period

Duarte¹,

Tanaka²,

Suzuki³

et al. 2013

An. Bras. Dermatol.

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“…Landeck, et al conducted a retrospective analysis of data from patient's patch tested in Germany, Austria and Switzerland (IVDK Network) between January 2001 and December 2010 and affirmed a frequency of contact sensitization to benzalkonium chloride to be 1.6% [8]. The frequency of contact sensitization to benzalkonium chloride was determined to be 1.2% in a cohort of 2,400 patients with chronic eczema tested between the years 2001 and 2009 in our department [21] and 1.85% rates in Sweden and Denmark are about 3 to 4% [4,5]. Such differences are due to variations in the availability and use of thimerosal-containing products in each country.…”

Section: Discussionmentioning

confidence: 85%

“…A group from Santa Casa of Belo Horizonte found that 14.7% of the 1,406 patients tested between 2003 and 2010 had positive thimerosal. Nevertheless, the report did not discuss the clinical relevance of the reactions [4]. Herbst, et al confirmed allergies to thimerosal in a group of patients with periorbital dermatitis in 10.2% of the patients, yet with no comment regarding relevance [7].…”

Section: Discussionmentioning

confidence: 96%

“…The high prevalence of thimerosal reactions in population resulted in the American Contact Dermatitis Society identifying the substance to become "allergen of the year" in 2002. However, in the same year Belsito published an article declaring thimerosal to be the "non-allergen of the year", because of a lack of clinical relevance of such reactions and recommended its exclusion from the American skin test battery [4,6]. A group from Santa Casa of Belo Horizonte found that 14.7% of the 1,406 patients tested between 2003 and 2010 had positive thimerosal.…”

Section: Discussionmentioning

confidence: 99%

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Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Nečas¹

2017

Int J Ophthalmol Clin Res

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Aims: 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization.Methods: A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results:The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion:The most important allergens in ophtalmologic products in our study were neomycin sulfate followed by benzalkonium chloride.With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient's actual ophtalmic preparations as well.

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“…Demograficamente, a exemplo do observado no presente trabalho em que a amostragem de pacientes com DC foi composta predominantemente por mulheres, tanto no grupo de idosos quanto no de não idosos, outros estudos nacionais também verificaram maior número amostral de pacientes do sexo feminino com DC [10,14,15]. Em relação à idade, existem poucos trabalhos abordando os quadros alérgicos em idosos [16][17][18][19][20][21][22][23][24][25][26][27][28][29], sendo que dois estudos nacionais apontaram uma alta prevalência de manifestações cutâneas nessa faixa etária, entre as quais a DC [21] e o prurido, como sintoma isolado [22].…”

Section: Discussionunclassified

Principais sensibilizantes em pacientes idosos e não idosos com dermatite de contato

Calamita

2016

Sci Med

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Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. Resultados: Foram incluídos 362 pacientes, entre o quais 60 idosos (idade maior ou igual a 60 anos) e 302 não idosos. Além da dermatite de contato foram observados outros tipos de alergias em 20 (33,3%) dos idosos e em 113 (37,4%) dos não idosos (p=0,54). Houve um total de 162 reações positivas ao patch test entre os idosos e 738 reações positivas entre os não idosos (p=0,24). Quanto às reações positivas fortes ocorreram 41 (68,3%) entre os idosos e 156 (51,6%) entre os não idosos (p=0,02). Somando-se reações positivas fortes e muito fortes, foram 44 (73,3%) em idosos e 214 (70,8%) em não idosos (p=0,69). As substâncias mais sensibilizantes foram o sulfato de níquel (em 33,3% dos idosos e 38 % dos não idosos) e o perfume mix (em 25% dos idosos e 27,8% dos não idosos), sem diferença estatística entre os dois grupos etários. Conclusões: A taxa de positividade do patch test entre os pacientes com dermatite de contato foi alta, não havendo diferença entre idosos e não idosos, sendo o sulfato de níquel e o perfume mix as substâncias mais sensibilizantes. Na investigação etiológica da dermatite de contato deve-se pensar principalmente na possibilidade de sensibilização aos perfumes e ao níquel, independentemente da faixa etária. DESCRITORES: dermatite de contato; idoso; perfumes; níquel; testes do emplastro. ABSTRACT Aims:To evaluate the prevalence of the main allergens found in allergic contact dermatitis among elderly and non-elderly patients. Methods: Retrospective study of the medical records of patients clinically diagnosed with contact dermatitis treated from August 2000 to January 2012 at the Allergy Outpatient Clinic of Marília Medical School and at an Allergy and Dermatology private clinic in Marília, state of São Paulo, Brazil. The inclusion criteria were clinical diagnosis of contact dermatitis, patch test performed during the study period, and no treatment with systemic corticosteroids or any other immunosuppressants. Age, sex, history of other types of allergy and allergens used were assessed. The patch test results were read 48 hours and 72 hours after application of the test chambers. Results: A total of 362 patients were included in the study: 60 elderly patients (aged 60 years or older) and 302 non-elderly patients. In addition to contact dermatitis, other types of allergies were observed in 20 (33.3%) of elderly patients and in 113 (37.4%) of non-elderly patients (p=0.54). There were 162 positive reactions on the patch test among elderly patients and 738 positive reactions among non-elderly patients (p=0.24). Strong positive reactions were present in 41 (68.3%) elderly patients and in 156 (51.6%) non-elderly patients (p=0.02). Strong and very strong positive reactions, when assessed together, were detected in 44 (73.3%) elderly patients and in 214 (70.8%) non-elderly patient...

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Results of Patch-Tests from Santa Casa de Belo Horizonte Dermatology Clinic, Belo Horizonte, Brazil, from 2003 to 2010

Cited by 14 publications

References 4 publications

Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period

Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Principais sensibilizantes em pacientes idosos e não idosos com dermatite de contato

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