Results of Radiotherapy for Chemodectomas

Schild, Steven E.; Foote, Robert L.; Buskirk, Steven J.; Robinow, Jay S.; Böck, F; Cupps, Roger E.; Earle, John D.

doi:10.1016/s0025-6196(12)60460-1

Cited by 66 publications

(39 citation statements)

References 27 publications

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“…Most patients become symptomatic, when the tumor is too big to be safely resected. Radiotherapy may be an option for patients with inoperable, residual or recurrent tumors [36][37]. Zabel et al published good tumor control rates and a low risk of morbidity in such patients [37].…”

Section: Discussionmentioning

confidence: 99%

Late outcome after surgical management of carotid body tumors from a 20-year single-center experience

Kotelis

Rizos

Geisbüsch

et al. 2008

Langenbecks Arch Surg

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Section: Discussionmentioning

confidence: 99%

Late outcome after surgical management of carotid body tumors from a 20-year single-center experience

Kotelis

Rizos

Geisbüsch

et al. 2008

Langenbecks Arch Surg

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“…Local control data for temporal bone chemodectomas from several representative surgical and RT series is shown in Tables 4 and 5, respectively. 16,17,[19][20][21][26][27][28][39][40][41][42][43][44][45][46] The likelihood of local control after either radiation or surgery is essentially the same.…”

Section: Discussionmentioning

confidence: 99%

Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale

et al. 2001

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“…The adequate dose can be considered to be 45-50 Gy. Clinical symptomatology after the radiotherapy can be ameliorated [8,25] in as many as 71% of patients [14]. A reduction in the size of the tumor can be achieved after radiotherapy in up to 61% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…Tumors arising from paraganglionic tissue usually grow slowly, and the interval from the first symptom to the diagnosis is usually between four to six years. Although this tumor can appear at any age, it is usually found between 50 and 60 years of age [1,3,[6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Leksell Gamma Knife Radiosurgery of the Tumor Glomus Jugulare and Tympanicum

Liščák

Vladyka

Šimonová

et al. 1998

Stereotact Funct Neurosurg

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We have treated 14 patients with glomus tumor during the 4 years (of 1993 to 1997) using Leksell Gamma Knife radiosurgery. The male: female ratio was 1:3.7, and the mean age 48.6 years (range 22–75 years). The mean tumor volume was 5.5 cm³ (range 0.7–11.3 cm³). The mean maximum dose was 37.4 Gy (range 20–44 Gy). The mean margin dose was 19.4 Gy (range 10–25 Gy). In 3 patients, infrabasal spread of the tumor could not be delineated on peroperative stereotactic CT scans. As a result, this portion of the tumor was treated in 2 patients at a second stage using stereotactic MRI. Follow-up in 11 patients ranged from 6 to 42 months (mean 20.5 months). Hearing on the affected side was further impaired in 3 patients. Tinnitus, vertigo and ataxia improved in 3 patients, headache and nausea in 2 patients. Angiography after radiosurgery was performed in 3 patients. In one patient 12 months after the radiosurgery, pathological vascularisation had completely disappeared. In another patient pathological vascularisation was still present 22 months after the first stage, despite two-stage radiosurgery, although the tumor volume decreased 30%. In the last patient, vascularisation and tumor volume partially decreased 12 months after radiosurgery. The volume of the tumor decreased in 4 patients. No change in tumor volume has been observed in any of the other patients to date. Radiosurgery proves to be a safe treatment for glomus tumor with no acute morbidity. Because of its naturally slow growth rate, up to 10 years follow-up will probably be necessary to establish the therapeutic effectiveness of radiosurgery for glomus tumor.

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Results of Radiotherapy for Chemodectomas

Cited by 66 publications

References 27 publications

Late outcome after surgical management of carotid body tumors from a 20-year single-center experience

Late outcome after surgical management of carotid body tumors from a 20-year single-center experience

Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale

Leksell Gamma Knife Radiosurgery of the Tumor Glomus Jugulare and Tympanicum

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